BD Pharmingen代理558447 PLK1 (pT210) Alexa 647 K50-483 50Tst;冷藏2-8°C

2025-06-21

货号:558447

品牌:BD Pharmingen

规格:50T

目录价:¥4378.00

市场价格:¥2758.14

会员价格:¥2407.90

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Polo-like kinase (PLK1) is a serine/threonine kinase with structural similarities to Drosophila’s Polo kinase and the Cdc5p of Saccharomyces cerevisiae. Like its invertebrate counterparts, PLK1 activity is required for DNA synthesis and is regulated throughout the cell cycle. Furthermore, PLK1 is highly expressed in primary tumors. It associates with the mitotic spindle during mitosis suggesting that, in addition to its role during S phase, PLK1 may play a role during chromosome segregation. This is consistent with its potential role in cancer development. Threonine 210 (T210) is one of the major phoshorylation sites in activated PLK1 obtained from human mitotic cells.The K50-483 monoclonal antibody recognizes the phosphorylated T210 of human PLK1.

Catalog Number
558447
Brand
BD Phosflow™
Name
PLK1 (pT210)
Size
50Tests
RegulatoryStatus
RUO
Clone
K50-483
Format
Alexa Fluor® 647
Isotype
IgG1, κ
W.B. Positive Control
none
Molecular Weight
68 kDa
Immunogen
Phosphorylated Human PLK1 Peptide
Reactivity
QC Testing : HumanPredicted : Mouse

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