货号：558503
品牌：BD Pharmingen
规格：1EA
目录价：￥5944.00
市场价格：￥3744.72
会员价格：￥3269.20
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The J148-1134 antibody reacts with interleukin-21 (IL-21), an ~ 15 kDa member of the type-I-cytokine family of proteins. IL-21 is expressed primarily by CD4+ T cells and has a broad range of immunoregulatory functions on B cells, CD8+ T cells, NK cells and dendritic cells. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of T cells and augmentation of antitumor activity of CD8+ T cells. It has been speculated that IL-21, through its varies positive and negative regulatory effects on cell-mediated and humoral immunity, may play a role in autoimmuninty, allergy, asthma and tumor regression.
- Catalog Number
- 558503
- Brand
- BD Pharmingen™
- Name
- IL-21
- Concentration
- 0.5 mg/ml
- Size
- 0.5mg
- RegulatoryStatus
- RUO
- Clone
- J148-1134
- Format
- Purified
- Isotype
- IgG1, κ
- W.B. Positive Control
- none
- Immunogen
- Human IL-21
- Reactivity
- Tested in Development : Human
- Applications
-
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