BD Pharmingen代理558643 Ms CD25 APC 3C7 100ug冷藏2-8°C

2025-06-21

货号:558643

品牌:BD Pharmingen

规格:1EA

目录价:¥5158.00

市场价格:¥3249.54

会员价格:¥2836.90

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Catalog Number
558643
Brand
BD Pharmingen™
Name
CD25
Alias
IL-2 Receptor α chain, p55
Concentration
0.2 mg/ml
Size
0.1mg
RegulatoryStatus
RUO
Clone
3C7
Format
APC
Isotype
IgG2b, κ
Immunogen
IL-2-dependent BALB/c mouse cell line
Strain Host
LEW
Reactivity
QC Testing : Mouse
Applications
Flow cytometry - Routinely Tested
Clone - Description

3C7 reacts with the 55 kDa low affinity (a chain, p55, CD25) IL-2 receptor subunit which is expressed by activated T and B lymphocytes from all mouse strains tested. The IL-2 receptor a chain (IL-2Ra) by itself is not a signaling receptor. However, the IL-2 receptor a chain can combine with IL-2 receptor b chains and gc chains to form high affinity, signaling receptor complexes for IL-2. Resting T and B lymphocytes and resting and activated NK cells do not express CD25. CD25 is transiently expressed at a low level during normal B-cell development at the Pre-B or Pre-B-II stage in the bone marrow, and it is expressed at a higher level during a very early stage of T cell development in fetal and adult thymus. The 3C7 antibody recognizes a CD25 epitope which is distinct from that recognized by the 7D4 antibody. The 3C7 antibody blocks the binding of IL-2 to CD25.1

Clone - Application

Flow Cytometry: Purified and PE- 3C7 are useful for immunofluorescent staining and flow cytometry.Neutralization: Purified NA/LE™ 3C7 is useful for neutralization.

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