货号：559931

品牌：BD Pharmingen

规格：1EA

目录价：￥6109.00

市场价格：￥3848.67

会员价格：￥3359.95

金山科研平台，产品价格货期咨询微信：jinshanbio

Catalog Number

559931

Brand

BD Pharmingen™

Name

GAD65

Concentration

0.5 mg/ml

Size

0.1mg

RegulatoryStatus

RUO

Clone

GAD-6

Format

Purified

Isotype

IgG_2a, κ

W.B. Positive Control

Rat Brain

Molecular Weight

65 kDa

Immunogen

Purified Rat GAD65

Reactivity

Tested in Development : HumanTested in Development : MouseQC Testing : RatTested in Development : Pig

Applications

Immunohistochemistry-frozen	- Reported
Immunoprecipitation	- Reported
Western Blot	- Routinely Tested

Clone - References

Kaufman, D.L, J.F. McGinnis, N.R. Krieger, and A.J. Tobin. 1986. Brain glutamate decarboxylase cloned in lambda gt-11: fusion protein produces gamma-aminobutyric acid. Science 232:1138-40.Bu, D.F., M.G. Erlander, B.C. Hitz, N.J.K. Tillakaratne, D.L. Kaufman, C.B. Wagner-McPherson, G.A. Evans, and A.J. Tobin. 1992. Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene. Proc Natl AEsclapez M., N.J. Tillakaratne, D.L. Kaufmann, A.J. Tobin, and C.R. Houser 1994. Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the foKanaani, J., D. Lissin, S.F. Kash, and S. Baekkeskov. 1999. The hydrophilic isoform of glutamate decarboxylase, GAD67, is targeted to membranes and nerve terminals independent of dimerization with the hydrophobic membrane-anchored isoform,Kim, J., W. Richter, H.J. Aanstoot, Y. Shi, Q. Fu, R. Rajotte, G. Wancok, and S. Baekkeskov. 1993. Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets. Diabetes 42:1799-1808.Hsu, C-C., C. Thomas, W. Chen, K.M. Davis, T. Foos, J.L. Chen, W. Wu, E. Floor, J.V. Schloss, and J-Y. Wu. 1999. Role of synaptic vesicle proton gradient and protein phosphorylation on ATP-mediated activation of membrane-associated brain glChang, Y-C. and D.I. Gottlieb. 1988. Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase. J Neurosci 8:2123-30.

Images