货号:081223
品牌:ThermoFisher /Invitrogen/ Gibco/ ABI
规格:6 ML
目录价:¥3074.00
市场价格:¥2766.60
会员价格:¥2766.60
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描述
This monoclonal antibody reacts with human epithelial cadherin (E-cadherin, uvomorulin, Cell-CAM 120/80), a 120 kDa transmembrane glycoprotein. Reduction and/or loss of E-cadherin expression in carcinomas correlates positively with tumor cell invasion and metastasis. Altered expression of E-cadherin is common in the progression of cancers including breast carcinoma, lung carcinoma, gastric tumors, hepatocellular carcinoma, and prostatic tumors. It has recently been reported that E-cadherin is a useful marker for differentiating lobular lesions (negative) from ductal invasive lesions (positive) in breast cancer. Positive tissue: Non-neural epithelia.Clone/PAD: 4A2C7Immunogen: Recombinant protein corresponding to the cytoplasmic domain of human E-cadherinSpecificity: Reacts strongly with human E-cadherin and weakly with human P-cadherin.Reactivity: HumanApplications: Immunohistochemistry (FFPE)Pretreatment: Epitope Retrieval: Required (Citrate Buffer, pH 6), Enzyme Digestion: Not requiredExpected Staining Pattern: Mainly cellular membrane, some cytoplasmic
规格
Reactivity: |
Human |
Validated Application: |
Immunohistochemistry (FFPE) |
Host: |
Mouse |
Target Gene: |
E-Cadherin |
Gene ID: |
999 |
Label or Dye: |
Unconjugated |
Dilution: |
2ndGen Predilute Antibody |
Product Size: |
6 mL |
Shipping Condition: |
Wet Ice |
内容及储存
Store in refrigerator (2–8°C).
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