货号：10752H08H5

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：5 UG

目录价：￥827.00

市场价格：￥744.30

会员价格：￥744.30

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 Manufactured by Sino Biological (China); Distributed by Life Technologies. Cluster of Differentiation 36 (CD36) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure the study of protein-protein interactions, and cell biology research applications. It can also be used as an immunogen, or as a protein standard.This recombinant protein is expressed from a DNA sequence encoding the extracellular domain (Gly 30-Asn 439) of human CD36 (NP_001001547.1) fused both to a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.N-terminal Sequence Analysis: Asp 31.Activity: measured by its binding ability in a functional ELISA . Immobilized human CD36 at 20 µg/mL (100 µL/well) has been shown to bind biotinylated human RSPO1 with a linear range of 0.032-4 µg/mL.Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween®-80.Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.Expiration Date: expires one year from date of receipt when stored as instructed.BackgroundCD36, is integral membrane protein found on the surface of many cell types in vertebrate animals. It belongs to the CD36 family and is found on platelets, erythrocytes, monocytes, differentiated adipocytes, mammary epithelial cells, spleen cells and some skin microdermal endothelial cells. CD36 has also been implicated in hemostasis, thrombosis, malaria, inflammation, lipid metabolism and atherogenesis. CD36 seems to have numerous potential physiological functions. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and binds long chain fatty acids. CD36 may also function as a cell adhesion molecule and in the transport and/or as a regulator of fatty acid transport. Defects in CD36 are the cause of platelet glycoprotein IV deficiency also known as CD36 deficiency. As a receptor for thrombospondin 1, CD36 plays a role in the regulation of angiogenesis, which may be a therapeutic strategy for controlling the dissemination of malignant neoplasms.You may also be interested in the following CD36 products: Primary AntibodiesGene Expression Assays 规格

Form:	Lyophilized
Purity:	≥ 85% by SDS-PAGE
Gene ID:	948
Species:	Human
Expression:	Mammalian
Gene Symbol:	CD36
Gene Aliases:	CD36, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3
Product Size:	5 µg
Protein Form:	Truncated,Recombinant,Cell Surface Protein
Protein Family:	CD Proteins
Endotoxin Level:	< 1 EU/µg
Protein Subtype:	Glycoproteins
Molecular Weight:	48 kDa
Research Category:	Signal Transduction,Drug Development,Oncology,Angiogenesis
Protein Tag or Fusion:	His Tag
Validated Application:	Assay Standard
Shipping Condition:	Room Temperature

内容及储存 Store at -20 to -70 °C