货号：4464064

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：HPLC/IVR

目录价：￥20184.00

市场价格：￥18165.60

会员价格：￥18165.60

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 miRNA mimics are small, chemically modified double-stranded RNA molecules designed to specifically bind to and mimic endogenous miRNA molecules and enable miRNA functional analysis by up-regulation of miRNA activity. Life Technologies has now released the second generation of miRNA mimics, mirVana™ miRNA Mimics, which: • Exhibit maximum and consistent effect in vitro at low concentration• Are non toxic• Offer superior specificity due to unique Star strand modification• Target the most updated Sanger content• Can be used in vitro and in vivo, offering you consistency throughout your entire research project Positive and negative controls are also available for use along with mirVana™ miRNA Mimics in miRNA up-regulation experiments.mirVana™ miRNA Mimic miR-1 Positive Control The mirVana™ miRNA Mimic miR-1 Positive Control is designed to mimic mature miR-1 miRNA after delivery to mammalian cells. miR-1 is associated with down-regulation of many genes. In particular, miR-1-mediated down-regulation of Protein Tyrosine Kinase 9 (PTK9) has been shown to occur at the mRNA level. miR-1 Positive Control is intended for use as a positive control for transfection experiments using mirVana™ miRNA Mimics. Monitor activity of miR-1 Positive Control through its gene silencing of PTK9, using real-time reverse transcription-PCR to detect PTK9 mRNA.First Generation Mimic Controls Our first-generation miRNA mimics (and controls), Ambion® Pre-miR™ miRNA Precursors, have lower specificity and potency, plus a lower strand specificity compared to the new mirVana™ miRNA Mimics. These first-generation mimics are recommended for completing ongoing in vitro miRNA studies. For new studies or in vivo studies, we highly recommend our new mirVana™ miRNA Mimics and their corresponding controls. 规格

RNAi Type:	Pre-miRNA
Control Type:	Positive Control
Label or Dye:	Unconjugated
Product Size:	50 nmol
Purification:	HPLC
Shipping Condition:	Room Temperature

内容及储存 Store at or below –20°C. Do not store in a frost-free freezer.