货号：480016

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：100 UL

目录价：￥4065.00

市场价格：￥3658.50

会员价格：￥3658.50

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 GABA_Α, α3-Subunit, Rabbit Polyclonal Antibody (SKU# 480016) is specific to Rat and Mouse. This antibody is validated for use in WB. GABAA , α3-Subunit, Rabbit Polyclonal Antibody recognizes the expressed product of the Gabra3 gene, also known as gamma-aminobutyric acid (GABA) A receptor, alpha 3, MGC33793, GABRA3.Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six αs, four βs and four γs, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for α- and β-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a γ-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different α-subunits of the receptor . 详细说明 常用规格

Reactivity:	Human, Rat
Validated Application:	Western Blot
Host:	Rabbit
SubClass (Isotype):	IgG1
Clonality:	Polyclonal
Clone ID:	pAB
Antibody Fragment:	Whole Antibody
Target Gene:	Gabra3
Gene ID:	2556, 24947
Gene Symbol:	GABRA3
Label or Dye:	Unconjugated
Purification:	Affinity Purified
Form:	Frozen
Product Size:	100 µl
Volume:	100 µl
Shipping Condition:	Wet Ice
Regulatory Statement:	For Research Use Only. Not for use in diagnostic procedures.

内容和储存

2-8°C for up to 1 month, -20°C for long term storage. Avoid repeated freezing and thawing.