货号:700258
品牌:ThermoFisher /Invitrogen/ Gibco/ ABI
规格:100 UG
目录价:¥4692.00
市场价格:¥4222.80
会员价格:¥4222.80
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描述
This purified ABfinity™ recombinant rabbit anti-connexin 30 monoclonal antibody is specific to mouse connexin 30. Anti-connexin 30 recognizes the expressed product of the GJB6 gene. Validated applications for this rabbit anti-connexin 30 monoclonal antibody are Western Blot, Immunofluorescence and Immunohistochemistry.Antibody Specifications:• Applications: Validated applications for rabbit anti-connexin 30 monoclonal antibody are Western Blot, Immunofluorescence and Immunohistochemistry.• Host Species and Isotype: The host species and isotype of the antibody is rabbit, IgG.• Clone ID of Monoclonal Antibody (mAb): The anti-connexin 30 monoclonal antibody clone is 16H9L8.• Reactivity: Reacts with mouse connexin 30.• Product Size: Rabbit anti-connexin 30 monoclonal antibody is available in a 100 µg size. Gap junctions are responsible for transport of ions and metabolites between adjacent cells. These structures are made of two hemi-channels, each formed by six connexin molecules. Connexin 30, coded by Cjb6 gene, is a member of the connexin family and is highly expressed in brain and skin. Immunohistochemically connexin 30 was localized in astrocytes, at gap junctions between these cells and on the astrocyte side of gap junctions between astrocytes and oligodendrocytes. Co-localization with connexin 43 was also observed in this study. The cytoskeleton, especially actin filaments, is an important component in the processes of assembly, trafficking and stabilization of connexin 30 gap junctions. Knock-out mice studies have also demonstrated that connexin 30 deficiency impairs renal tubular ATP release and pressure natriuresis highlighting the importance of this molecule in kidney. Further, in vitro studies have also demonstrated that connexin 30 overexpression enhances cell proliferation.
规格
Reactivity: |
Mouse |
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Validated Application: |
Western Blot,Immunofluorescence,Immunohistochemistry |
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Host: |
Rabbit |
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SubClass (Isotype): |
IgG |
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Clonality: |
Monoclonal |
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Clone ID: |
16H9L8 |
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Antibody Fragment: |
Whole Antibody |
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Target Gene: |
Connexin 30 |
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Gene ID: |
14623 |
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Accession Number: |
P70689 |
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Label or Dye: |
Unconjugated |
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Purification: |
Affinity Purified |
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Concentration: |
0.5 mg⁄ml |
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Form: |
Liquid |
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Neutralizing Antibody: |
No |
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Platform: |
Fluorescence Microscope,Confocal Microscope |
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Product Size: |
100 µg |
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Quantity: |
1 |
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Volume: |
200 µl |
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Shipping Condition: |
Approved for shipment on Wet or Dry Ice |
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内容及储存
2-8°C for up to 1 month, -20°C for long term storage. Avoid repeated freezing and thawing.
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© ThermoFisher /Invitrogen/ Gibco/ ABI代理700258 CONNEXIN 30 REC RB MAB:Store:FR : Freezer (-5 to -3 C),产品报价联系微信jinshanbio
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