货号：700727

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：EACH

目录价：￥4692.00

市场价格：￥4222.80

会员价格：￥4222.80

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 This purified ABfinity™ recombinant rabbit monoclonal antibody, clone 4H15L5, recognizes GATA1 protein in human.ABfinity™ antibody characteristics include:• Validation in Western blot• Superior lot-to-lot consistency• Extremely high specificity and sensitivity• Recombinant rabbit monoclonal antibodyClone ID: 4H15L5Specific for GATA1GATA is a family of proteins that plays a very important role in translating various signaling pathways controlling proliferation and differentiation of erythroid progenitor cells (Ref 1). There are 6 transcription factors in the GATA family: GATA 1 to GATA 6. GATA 1 plays a key role in blood cell differentiation by binding to DNA and interacting with other proteins to regulate growth and proliferation (Ref 2). The gene encoding GATA 1 is found on the X chromosome (Ref 3).Exceptional Consistency Saves You Time and MoneyABfinity™ antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with the highest consistency between lots, eliminating the need to revalidate your assays for each lot.High Specificity Means More Reliable DataThe proprietary recombinant technology employed in the production of ABfinity™ antibodies means you are assured of the greatest degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved. Invitrogen has validated this antibody in Western blotting.High Sensitivity Lets You Detect Low Levels of Target ProteinABfinity™ antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed in low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.Recombinant Rabbit IgG—Use Like Any Other IgG AntibodyAs with traditional IgG antibodies, gel electrophoresis of ABfinity™ antibodies produces a 150 kDa band under non-reducing conditions and 50 kDa and 25 kDa bands under reducing conditions.For research use only. Not intended for any human or animal therapeutic or diagnostic use.Related Links:Learn more about the superior performance of ABfinity™ recombinant monoclonal antibodiesSee Invitrogen's full line of ABfinity™ recombinant monoclonal antibodiesReferences1. Briegel K, Bartunek P, Stengl G, Lim KC, Beug H, Engel JD, Zenke M. Regulation and function of transcription factor GATA-1 during red blood cell differentiation. Development. 1996 Dec;122(12):3839-50. PubMed PMID: 9012505.2. Ferreira R, Ohneda K, Yamamoto M, Philipsen S. GATA1 function, a paradigm for transcription factors in hematopoiesis. Mol Cell Biol. 2005 Feb;25(4):1215-27. PubMed PMID: 15684376.3. Fujiwara Y, Browne CP, Cunniff K, Goff SC, Orkin SH. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12355-8. PubMed PMID: 8901585. 规格

Validated Application:	ELISA,Western Blot
Host:	Rabbit
SubClass (Isotype):	IgG
Clonality:	Monoclonal
Clone ID:	4H15L5
Antibody Fragment:	Whole Antibody
Gene ID:	2623
Accession Number:	P15976
Label or Dye:	Unconjugated
Purification:	Purified
Form:	Liquid
Mass:	100 µg
Neutralizing Antibody:	No
Product Size:	100 µg
Protein Family:	Transcription Factors
Research Category:	Signal Transduction
Shipping Condition:	Approved for shipment on Wet or Dry Ice

内容及储存 2-8°C for up to 1 month, -20°C for long term storage. Avoid repeated freezing and thawing.