货号：701066

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：EACH

目录价：￥4692.00

市场价格：￥4222.80

会员价格：￥4222.80

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 This purified ABfinity™ recombinant rabbit anti-LRRK2 [pS395] monoclonal antibody is specific to human LRRK2 [pS395]. LRRK2 (Leucine-Rich Repeat Kinase 2), an enzyme commonly known as Dardarin, belongs to the leucine-rich repeat kinase family. The LRRK2 gene is active in brain and other tissues. This rabbit anti-LRRK2 [pS395] monoclonal antibody is used in western blotting and ELISA applications.Antibody Specifications:• Applications: Validated applications for anti-LRRK2 [pS395] monoclonal antibody are western blotting and ELISA.• Host Species and Isotype: The host species and isotype of the antibody is rabbit IgG.• Clone ID of Monoclonal Antibody (mAb): The anti-LRRK2 [pS395] monoclonal antibody clone is 3H8L19.• Reactivity: Reacts with human LRRK2 [pS395].• Product Size: Rabbit anti-LRRK2 [pS395] monoclonal antibody is available in a 100 µg size. LRRK2 (Leucine-Rich Repeat Kinase 2), an enzyme commonly known as Dardarin, belongs to the leucine-rich repeat kinase family. The LRRK2 gene is active in brain and other tissues. A part of the gene provides instructions for synthesis of a protein segment that is rich in leucine. Proteins with leucine-rich regions appear to play a role in activities requiring protein-protein interactions, such as transmitting signals or helping to assemble the cell's structural framework. LRRK2 also possesses a GTPase activity. Phosphorylation at specific sites (e.g. serine 910 and serine 935) determines 14-3-3 binding to LRRK2; 14-3-3 is a regulator of LRRK2-mediated cellular activities. Anomalies in the LRRK2 gene are associated with Parkinson's disease. In humans, the gene encoding LRRK2 is present on the q arm of chromosome 12. 规格

Reactivity:	Human
Validated Application:	ELISA,Western Blot
Host:	Rabbit
SubClass (Isotype):	IgG
Clonality:	Monoclonal
Clone ID:	3H8L19
Antibody Fragment:	Whole Antibody
Target Gene:	LRRK2 [pS935]
Gene ID:	120892
Gene Symbol:	LRRK2
Accession Number:	Q17RV3
Label or Dye:	Unconjugated
Purification:	Purified
Concentration:	0.5 mg⁄ml
Form:	Liquid
Neutralizing Antibody:	No
Product Size:	100 µg
Protein Family:	Kinases & Inhibitors
Shipping Condition:	Wet Ice

内容及储存 2 - 8°C for up to 1 month -20°C for long storage Avoid repeated freezing and thawing.