货号：701261

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：EACH

目录价：￥4692.00

市场价格：￥4222.80

会员价格：￥4222.80

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 This purified ABfinity™ recombinant rabbit monoclonal antibody recognizes p70S6K in human samples.ABfinity™ antibody characteristics include:• Validation in Western Blot, Immunofluorescence and Flow Cytometry• Superior lot-to-lot consistency• Extremely high specificity and sensitivity• Recombinant rabbit monoclonal antibody• Specific for p70S6KThe p70 S6 is the ribosomal S6 protein kinase is known for its role in modulating cell-cycle progression (for cell growth and G1 cell cycle progression), cell size, and cell survival. In response to mitogen stimulation, p70 S6 kinase activation up-regulates ribosomal biosynthesis and enhances the translational capacity of the cell. p70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5′ oligopyrimidine tract mRNAs. The activity of p70 S6 kinase is controlled by multiple phosphorylation events located within its catalytic, linker, and pseudosubstrate domains. It is phosphorylated and activated by mTOR in mitogenic pathways downstream from phosphoinositide 3-kinase.Exceptional Consistency Saves You Time and MoneyABfinity™ antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with the highest consistency between lots, eliminating the need to revalidate your assays for each lot.High Specificity Means More Reliable DataThe proprietary recombinant technology employed in the production of ABfinity™ antibodies means you are assured of the greatest degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved. Life Technologies has validated this antibody in Western Blot, Immunofluorescence and Flow Cytometry.High Sensitivity Lets You Detect Low Levels of Target ProteinABfinity™ antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed in low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.Recombinant Rabbit IgG–Use Like Any Other IgG AntibodyAs with traditional IgG antibodies, gel electrophoresis of ABfinity™ antibodies produces a 150 kDa band under non-reducing conditions and 50 kDa and 25 kDa bands under reducing conditions.For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.Related Links:Learn more about the superior performance of ABfinity™ recombinant monoclonal antibodies.See Life Technologies's full line of ABfinity™ recombinant monoclonal antibodies. 规格

Reactivity:	Human
Validated Application:	Flow Cytometry,Immunofluorescence,Western Blot
Host:	Rabbit
SubClass (Isotype):	IgG
Clonality:	Monoclonal
Clone ID:	15H5L2
Antibody Fragment:	Whole Antibody
Gene ID:	6198
Gene Symbol:	RPS6KB1
Gene Aliases:	S6K; PS6K; S6K1; STK14A; p70-S6K; p70-alpha; p70(S6K)-alpha
Label or Dye:	Unconjugated
Purification:	Affinity Purified
Concentration:	0.5 mg⁄ml
Form:	Liquid
Product Size:	100 µg
Volume:	200 µl
Research Category:	Signal Transduction
Shipping Condition:	Wet Ice

内容及储存 2 - 8 °C for up to 1 month, -20 °C for long storage. Avoid repeated freezing and thawing.