货号：701285

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：EACH

目录价：￥4692.00

市场价格：￥4222.80

会员价格：￥4222.80

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 This purified ABfinity™ recombinant rabbit monoclonal antibody (mAb) recognizes MMP3 in human samples.ABfinity™ antibody characteristics include:• Validation in immunocytochemistry, western blot, and indirect ELISA• Superior lot-to-lot consistency• Extremely high specificity and sensitivity• Recombinant rabbit monoclonal antibody• Specific for MMP3 MMP3 (matrix metalloproteinase 3) also known as stromelysin 1 is encoded by the MMP3 gene located on chromosome 11. It belongs to the peptidase M10 A family of proteins. MMP3 is generally secreted in its pro-protein form and is activated by extracellular proteinases cleavage (1). The active enzyme that is so formed degrades collagen, gelatin, fibronectin, and laminin. MMP3 is also involved in normal cellular processes such as wound repair and tissue remodeling. MMP3 is capable of binding to zinc ions, calcium ions, and has metalloendopeptidase activity.Exceptional Consistency Saves You Time and MoneyABfinity™ antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with the highest consistency between lots, eliminating the need to revalidate your assays for each lot.High Specificity Means More Reliable DataThe proprietary recombinant technology employed in the production of ABfinity™ antibodies means you are assured of the greatest degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved. Life Technologies has validated this antibody in western blotting.High Sensitivity Lets You Detect Low Levels of Target ProteinABfinity™ antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed in low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.Recombinant Rabbit IgG - Use Like Any Other IgG AntibodyAs with traditional IgG antibodies, gel electrophoresis of ABfinity™ antibodies produces a 150 kDa band under non-reducing conditions and 50 kDa and 25 kDa bands under reducing conditions.Related Links:Learn more about the superior performance of ABfinity™ recombinant monoclonal antibodies.See Life Technologies' full line of ABfinity™ recombinant monoclonal antibodies.References:

1. Stepwise activation mechanisms of the precursor of matrix metalloproteinase 3 (stromelysin) by proteinases and (4-aminophenyl) mercuric acetate. Nagase H., Enghild J.J., Suzuki K., Salvesen G. Biochemistry 29, 5783-5789 (1990) [PubMed:2383557].

规格

Reactivity:	Human
Validated Application:	Flow Cytometry,Western Blot,Immunocytochemistry,ELISA
Host:	Rabbit
SubClass (Isotype):	IgG
Clonality:	Monoclonal
Clone ID:	45H6L22
Antibody Fragment:	Whole Antibody
Target Gene:	Matrix Metallopeptidase 2
Gene ID:	4313
Gene Symbol:	MMP2
Accession Number:	P08254
Gene Aliases:	Stromelysin-1, Transin-1, STMY-1
Label or Dye:	Unconjugated
Concentration:	0.5 mg⁄ml
Form:	Liquid
Product Size:	100 µg
Protein Family:	Proteases, Peptidases & Inhibitors
Buffer:	PBS (Phosphate Buffered Saline)
Research Category:	Oncology,Inflammation
Other Additives:	Sodium Azide Preservative

内容及储存 2 - 8 °C for up to 1 month, -20 °C for long storage. Avoid repeated freezing and thawing.