货号：11-0791-82
品牌：eBioscience (含Bender)
规格：100 ug
目录价：￥1788.00
市场价格：￥1519.80
会员价格：￥1484.04
金山科研平台，产品价格货期咨询微信：jinshanbio
Description: This 24C2.5 monoclonal antibody reacts with the intracellular tail of mouse CD79a (also known as Ig alpha or mb-1), a signaling component of the B cell receptor (BCR). CD79a heterodimerizes with CD79b (Ig beta, B29), and together with surface Ig, make up the BCR. Both CD79 subunits consist of a single extracellular Ig domain, a transmembrane domain, and an intracellular signaling domain. CD79a is expressed almost exclusively on B cells, as well as in most B lineage acute lymphoblastic leukemias. The cytoplasmic domain of CD79a contains immunoreceptor tyrosine-based activation motifs (ITAMs), which constitute the signal transducing portions of the BCR. Tyrosine phosphorylation of these ITAMs by Syk and Lyn initiates numerous signaling cascades, resulting in B cell activation, proliferation, and differentiation.
| Host |
Mouse |
|---|
| Isotype |
IgG1, kappa |
|---|
| Reactivity |
Mouse |
|---|
| Conjugate |
FITC |
|---|
| Laser |
Blue Laser |
|---|
| Emit |
518 nm |
|---|
| Excite |
488 nm |
|---|
| Reported Applications |
Intracellular Staining Followed by Flow Cytometric Analysis |
|---|
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