货号：12-5783-81
品牌：eBioscience (含Bender)
规格：50ug
目录价：询价
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Description: The eBio12A8 antibody reacts with Ly-49A and Ly-49D. The Ly-49 family of NK-cell receptors, members of the C-type lectin superfamily, are disulfide-linked type-II transmembrane protein homodimers with extracellular carbohydrate-recognition domains which bind to MHC class I alloantigens. The Ly-49 family members are expressed independently, such that an individual NK or T cell may display more than one class of Ly-49 receptor homodimers. Ly-49D is expressed on subsets of natural killer cells in C57BL/6, C3H/He, and SJL mice, but not DBA/2, AKR, CBA/J, or BALB/c mice. The Ly-49D antigen has not been detected on NK-1.1+ T cells. The Ly-49D receptor has been implicated in mediation of NK cell cytolysis. Ly-49D is an activating receptor while Ly-49A is a inhibitory receptor. eBio12A8 does not react with BALB/c, DBA/2, AKR, or CBA/J Ly-D49D.
| Host |
Rat |
|---|
| Isotype |
IgG2a, kappa |
|---|
| Reactivity |
Mouse |
|---|
| Conjugate |
PE |
|---|
| Laser |
Blue Laser, Green Laser, Yellow-Green Laser |
|---|
| Emit |
575 nm |
|---|
| Excite |
488 - 561 nm |
|---|
| Reported Applications |
Flow Cytometric Analysis |
|---|
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