eBioscience (含Bender)代理12-5867-42 Anti-Human/Mouse Integrin beta 7 PE 100 tests；价格见Thermo同编号产品-试剂-金山科研平台

eBioscience (含Bender)代理12-5867-42 Anti-Human/Mouse Integrin beta 7 PE 100 tests；价格见Thermo同编号产品

2025-06-28

货号：12-5867-42

品牌：eBioscience (含Bender)

规格：100tests

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio

Description: The FIB504 monoclonal antibody reacts with human and mouse integrin beta 7. Integrin beta 7 is a 130 kD glycoprotein which associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin alpha 4 beta 7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alpha E beta 7 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.

Host	Rat
Isotype	IgG2a, kappa
Reactivity	Human, Mouse
Conjugate	PE
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Emit	575 nm
Excite	488 - 561 nm
Reported Applications	Flow Cytometric Analysis

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