BD IS代理340366 CD2/CD2R纯化试剂

2025-06-28

货号:340366

品牌:BD IS

规格:250ug

目录价:¥7561.00

市场价格:¥5292.70

会员价格:¥4914.65

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A combination of purified comitogenic monoclonal antibodies for use as a T-lymphocyte activation control.The CD2 molecule is an Mr 50-kDa human lymphocyte antigen. At least three different functional epitopes of CD2 have been defined. One epitope (recognized by clone S5.2) is the sheep red blood cell (SRBC) receptor. The other two epitopes, CD2 and CD2R, are binding sites for monoclonal antibodies that, when used together, deliver signals for polyclonal T-lymphocyte activation.The CD2 epitope recognized by clone L303.1 is expressed on essentially all resting and activated T lymphocytes and on a subset of resting and activated NK lymphocytes. The CD2R epitope recognized by clone L304.1 is expressed at lower levels on resting T cells. Upon activation, CD2R becomes more accessible to antibodies, most likely due to a conformational change.

Catalog Number
340366
Brand
BD FastImmune™
Name
CD2/CD2R
Size
250µg
RegulatoryStatus
RUO (GMP)
Clone Format Isotype
L303.1PurifiedMouse IgG2a
L304.1PurifiedMouse IgG1

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