货号：340422

品牌：BD IS

规格：50T

目录价：￥7596.00

市场价格：￥5317.20

会员价格：￥4937.40

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Catalog Number

340422

Name

CD4 v4

Size

50Tests

RegulatoryStatus

RUO (GMP)

Clone

L120

Format

FITC

Isotype

IgG₁, κ

W.S. No

none

W.B. Positive Control

none

Molecular Weight

none

Reactivity

QC Testing : Human

Applications

Flow cytometry

- Routinely Tested

Clone - Description

CD4, clone L120, recognizes an antigen approximately 59 kDa that is present on the helper/inducer subset of T lymphocytes and monocytes. The CD4 antigen is involved in the class II recognition of foreign antigens and has been identified as a receptor for human immunodeficiency virus (HIV). Clone L120 recognizes amino acids 306 to 370 of the antigen and does not block the binding of the gp120 of HIV, but inhibits the proliferation of CD4 T lymphocytes to class II antigens.The CD4 antigen is present on most thymocytes, approximately 40% of peripheral blood lymphocytes, and at lower density on monocytes. Peripheral blood CD4⁺ lymphocytes are lost over time during HIV infection, and this loss is correlated with disease progression.