货号：340483

品牌：BD IS

规格：50T

目录价：￥4964.00

市场价格：￥3474.80

会员价格：￥3226.60

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Catalog Number

340483

Name

NKB1

Alias

KIR

Size

50Tests

RegulatoryStatus

RUO (GMP)

Clone

DX9

Format

FITC

Isotype

IgG₁, κ

Reactivity

QC Testing : Human

Applications

Flow cytometry

- Routinely Tested

Clone - Description

Anti-human killer inhibitory receptor (KIR), NKB1, (Anti-Hu KIR [NKB1]) recognizes a 70-kDa glycoprotein that is a member of the p58/NK-associated transcript (NKAT) family of class I receptors. KIR (NKB1) is an MHC class I receptor that inhibits NK cell–mediated cytotoxicity on target cells that express HLA-B molecules of the Bw4 serotype, but it does not affect recognition of HLA-A or HLA-C antigens. KIR (NKB1)-mediated inhibition is abrogated by binding of Anti-Hu KIR (NKB1). Anti-Hu KIR (NKB1) also regulates T-cell activation initiated through the T-cell antigen receptor (TCR) complex. KIR (NKB1) is expressed on a subset of human NK cells (CD3^-/CD56⁺), NK cell clones, and a subset of human T lymphocytes.