货号：341644

品牌：BD IS

规格：50T

目录价：￥4565.00

市场价格：￥3195.50

会员价格：￥2967.25

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Catalog Number

341644

Name

CD30

Alias

Ki-1

Size

50Tests

RegulatoryStatus

RUO (GMP)

Clone

Ber-H83

Format

FITC

Isotype

IgG₁, κ

W.S. No

none

W.B. Positive Control

none

Molecular Weight

none

Reactivity

QC Testing : Human

Applications

Flow cytometry

- Routinely Tested

Clone - Description

CD30 recognizes a 120-kilodalton (kd) type I transmembrane glycoprotein. The CD30 antigen belongs to the tumor necrosis factor receptor/nerve growth factor receptor (TNFR/NGFR) superfamily.The CD30 antigen is a receptor and an activation marker. It is expressed by a small subset of extrafollicular activated T and B cells, B cells at the rim of germinal centers, lung macrophages, activated natural killer (NK) cells, endothelial cells, and decidual cells. CD30 antigen is present on primary and cultured Hodgkin’s and Reed-Sternberg cells and might aid in the differential diagnosis of Hodgkin’s disease. It is also found on major categories of non-Hodgkin’s lymphomas, particularly anaplastic large-cell lymphoma (ALCL), adult T-cell leukemia, and embryonic carcinomas. CD30 interaction with CD30 ligand (CD30L) can elicit multidirectional signals leading to either activation or apoptosis.