货号：347196

品牌：BD IS

规格：100T

目录价：￥7704.00

市场价格：￥5392.80

会员价格：￥5007.60

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Catalog Number

347196

Name

Terminal-Deoxynucleotidyl Transferase (TdT)

Alias

TdT

Size

100Tests

RegulatoryStatus

RUO (GMP)

Clone

E17-1519

Format

APC

Isotype

IgG₁, κ

W.S. No

none

W.B. Positive Control

none

Molecular Weight

none

Reactivity

QC Testing : Human

Applications

Flow cytometry	- Routinely Tested
Intracellular Staining	- Routinely Tested

Clone - Description

Anti–terminal-deoxynucleotidyl transferase (TdT) recognizes a 60-kilodalton (kd) polymerase, a nuclear enzyme that catalyzes the template-independent addition of nucleotides to single-stranded DNA primers. It has been reported that TdT is involved in the regulation or translocation or both of DNA and gene rearrangement during normal T- and B-cell development.TdT is present in nuclei of immature T and B lymphocytes found in normal thymus and bone marrow. Some neoplastic cells of acute lymphoblastic lymphoma/leukemia have been shown to have high TdT activity. Mature lymphocytes from normal peripheral blood usually do not contain the enzyme.