货号：LIF1050

品牌：Merck Millipore

规格：50Ug

目录价：￥10260.00

市场价格：￥8721.00

会员价格：￥8208.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Leukemia Inhibitory Factor, recombinant human View All» Trade Name: Chemicon (Millipore) View All» Qty/Pk: 50 µg View All» Product Overview: Leukemia Inhibitory Factor (LIF) is a lymphoid factor which promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has a number of other activities including cholinergic neuron differentiation, control of stem cell pluripotency, bone and fat metabolism, mitogenesis of certain factor dependent cell lines and promotion of megakaryocyte production in vivo. Human LIF is a 19.7 kDa protein containing 181 amino acid residues. View All» Key Applications: Cell Culture View All» Usage Statement:

• Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

• LABEL LICENSE - USE RESTRICTED TO RESEARCH USE ONLYLeukemia Inhibitory Factor ("LIF") is protected by US Patents No. 5,443,825 and 5,750,654 and Canada Patent No. 1,341,581 and 1,341,469 owned by AMRAD Corporation Ltd. and licensed exclusively to Millipore for research uses. The use of this product is limited for research uses only and not for any commercial purposes, such as making or developing other research products from this product or use of this product as a component in a research kit. This product is not to be used in humans or for any diagnostic purposes.The purchaser may refuse to accept the conditions of this label license by returning this product unopened and will receive a full refund of the purchase price paid.For-profit entities or commercial research entities purchasing this product shall be required to execute a separate commercial license with Millipore within three months of purchase. Researchers may not transfer this product or its derivatives to researchers performing commercial research at other Nonprofit Organizations, or to For-Profit Organizations, without the express written consent of Millipore, and without those entities having an express license from Millipore for the use of the product. Other than as specifically provided herein, a transferee of this product shall have no right to transfer this product, or its derivatives to any other person or entity.
  View All» Entrez Gene Summary: Leukaemia inhibitory factor is a cytokine that induces macrophage differentiation. Neurotransmitters and neuropeptides, well known for their role in the communication between neurons, are also capable of activating monocytes and macrophages and inducing chemotaxis in immune cells. LIF signals through different receptors and transcription factors. LIF in conjunction with BMP2 acts in synergy on primary fetal neural progenitor cells to induce astrocytes. View All» UniProt Summary: FUNCTION: SwissProt: P15018 # LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.SIZE: 202 amino acids; 22008 Da SUBCELLULAR LOCATION: Secreted.SIMILARITY: SwissProt: P15018 ## Belongs to the LIF/OSM family. View All» Species: Human View All» Brand Family: Chemicon View All» Source: hLIF is expressed in E. coli as a fusion protein with GST using the pGEX expression system, cleaved from GST moeity with thrombin and purified by HPLC chromatography. View All» Presentation: Liquid in PBS, pH 7.4 and 0.02% Tween 20. No preservatives added. View All» Storage Conditions: Maintain at 2-8°C for 6-12 months. Further dilutions should be made into buffer or medium to which protein (e.g., 1% BSA) or Tween 20 has been added. View All» Gene Symbol:
  • LIF

  • Emfilermin

  • MLPLI

  • HILDA

  • D-FACTOR

  • CDF
    View All» Product Name: Leukemia Inhibitory Factor, recombinant human View All» Alternate Names: LIF View All» Concentration: 100 μg/mL View All» UniProt Number: P15018 View All» Specific Activity: The activity of human LIF is determined by the ability to induce differentiation of M1 myeloid leukemic cells. The minimum detectable concentration of human LIF in this assay is 0.5 ng/mL. The specific activity is >=1 x 10(E8) units/mg, where 50 units is defined as the amount of human LIF required to induce differentiation in 50% of the M1 colonies in 1 mL agar cultures. View All» Entrez Gene Number: NM_002309.2 View All» Purity: Greater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per mg of LIF. Tested negative in both aseptic and mycoplasmic tests. View All»
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