货号：MAB10009

品牌：Merck Millipore

规格：100Ug

目录价：￥6127.00

市场价格：￥5207.95

会员价格：￥4901.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-IDO Antibody, clone 1F8.2 | MAB10009 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes IDO. View All» Molecular Weight: Approx. 45 kDa View All» Immunogen: GST-tagged recombinant protein of full-length human IDO. View All» Clone: 1F8.2 View All» Isotype: IgG1κ View All» Background Information: Indoleamine 2,3-dioxygenase (IDO) is an enzyme that is responsible for converting tryptophan to kynurenines. IDO is expressed by a wide variety of tissues and IDO can be upregulated by interferon gamma. IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO may be involved in thesuppression of the immune response to tumours and blocking the IDO pathway may be a potential target for immunotherapy. View All» Species Reactivity: Human View All» Species Reactivity Note: Proven to react with human. View All» Control: HeLa cell lysate treated with interferon gamma. View All» Quality Assurance: Evaluated by Western Blot in HeLa cell lysate.Western Blot Analysis: 0.1 µg/mL dilution of this antibody detected IDO on 15 µg of HeLa cell lysate. View All» Purification Method: Protein G purfied View All» Presentation: Mouse monoclonal in buffer containing 0.1 M Tris-glycine, pH 7.4, 150 mM NaCl and 0.05% sodium azide. View All» Storage Conditions: Maintain refrigerated at 2-8°C for 1 year from date of receipt. View All» UniProt Number: P14902 View All» Entrez Gene Number: NP_002155.1 View All» Gene Symbol:

• CD107B

• EC 1.13.11.52

• IDO

• INDO
  View All» Alternate Names:
  • Indoleamine-pyrrole 2,3-dioxygenase

  • indole 2,3-dioxygenase

  • indoleamine 2,3-dioxygenase 1

  • indoleamine-pyrrole 2,3 dioxygenase
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» UniProt Summary: FUNCTION: Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.CATALYTIC ACTIVITY: D-tryptophan + O2 = N-formyl-D-kynurenine.L-tryptophan + O2 = N-formyl-L-kynurenine.COFACTOR: Binds 1 heme group per subunit.INDUCTION: By interferon gamma.SEQUENCE SIMILARITIES: Belongs to the indoleamine 2,3-dioxygenase family. View All» Product Name: Anti-IDO, clone 1F8.2 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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      © Merck Millipore代理MAB10009 Anti-IDO Antibody, clone 1F8.2;store at +2℃ to +8℃，产品报价联系微信jinshanbio