货号：MAB10083

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-SP3, clone 3F2 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Molecular Weight: 82 kDa View All» Immunogen: Recombinant human SP3 View All» Isotype: IgG1 View All» Background Information: The gene for SP3 belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. View All» Species Reactivity:

• Human

• Mouse
  View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Presentation: Liquid containing 0.1% sodium azide. View All» Storage Conditions: 1 year at 2-8°C from date of shipment View All» UniProt Number: Q02447 View All» Entrez Gene Number:
  • NM_001017371.3

  • NM_003111.3
    View All» Gene Symbol:
    • SP3

    • SPR-2

    • DKFZp686O1631
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. View All» UniProt Summary: FUNCTION: SwissProt: Q02447 # Transcriptional factor that can act as an activator or repressor, probably in a isoform-specific manner. Binds to GT and GC boxes promoters elements.SIZE: 781 amino acids; 81925 Da SUBCELLULAR LOCATION: Nucleus.TISSUE SPECIFICITY: Ubiquitously expressed.SIMILARITY: SwissProt: Q02447 ## Belongs to the Sp1 C2H2-type zinc-finger protein family. & Contains 3 C2H2-type zinc fingers. View All» Brand Family: Chemicon View All» Product Name: Anti-SP3, clone 3F2 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Culture Supernatant View All» Host: Mouse View All»
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