货号：MAB10111

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Cytochrome P450 4F11 Antibody, clone F21 P6 F5 | MAB10111 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the C-terminus of Cytochrome P450 4F11. View All» Molecular Weight: ~ 57 kDa View All» Epitope: C-terminus View All» Immunogen: Ovalbumin-conjugated linear peptide corresponding to the C-terminus of human Cytochrome P450 4F11. View All» Clone: F12 P6 F5 View All» Isotype: IgG1κ View All» Background Information: Cytochrome P450 4F11, as a monooxygenase, is involved in catalyzing several reactions that take place in drug metabolism and the production of steroids, cholesterol, and other lipids. It is located in the Endoplasmic Reticulum membrane and has been found mainly in human liver, skeletal muscle, heart and kidney. Cytochrome P450 is the most important element of oxidativemetabolism. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with human. View All» Control: Human liver tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human liver tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected Cytochrome P450 4F11 on 10 µg of human liver tissue lysate. View All» Purification Method: Protein G purfied View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9HBI6 View All» Entrez Gene Number: NP_001122404 View All» Gene Symbol:

• CYPIVF11

• CYP4F11
  View All» Alternate Names:
  • cytochrome P450 family 4 subfamily F polypeptide 11

  • cytochrome P450, family 4, subfamily F, polypeptide 11

  • cytochrome P450, subfamily IVF, polypeptide 11
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]. View All» UniProt Summary: CATALYTIC ACTIVITY: RH + reduced flavoprotein + O2 = ROH + oxidized flavoprotein + H2O.COFACTOR: Heme group by similarity.SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein By similarity. Microsome membrane; Single-pass membrane protein By similarity. TISSUE SPECIFICITY: Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle.SEQUENCE SIMILARITIES: Belongs to the cytochrome P450 family.SEQUENCE CAUTION: The sequence AAC27731.1 differs from that shown. Reason: Erroneous gene model prediction. View All» Product Name: Anti-Cytochrome P450 4F11, clone F21 P6 F5 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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