货号：MAB10401

品牌：Merck Millipore

规格：

目录价：￥3990.00

市场价格：￥3391.50

会员价格：￥3192.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Plexin-D1 Antibody, clone 19C6.1 | MAB10401 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~250 kDa observed. This protein is glycosolated and runs higher than the calculated molecular weight of 212 kDa. View All» Immunogen: Recombinant protein corresponding to human Plexin-D1. View All» Clone: 19C6.1 View All» Isotype: IgG1κ View All» Background Information: Plexin-D1 is a member of the plexin family of proteins and is a 1925 amino acid long protein that is encoded by the PLXND1 gene. It is active during embryogenesis and is gradually lost during development. It is thought tp play a part in Mobius syndrome 2, a genetic defect that paralyses the facial nerves. Plexin-D1 is most commonly expressed in the central nervous system and vascular endothelium. Inactivation of Plexin-D1 is also thought to be the cause of a certain type of congenital heart disease. In a mouse model, Plexin-D1 expression is recovered during tumor angiogenesis of brain metastasis and may be a clinically relevant marker. Plexin-D1 also plays a role in blood vessel patterning and axial skeletogenesis. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with human. View All» Control: HEK293 cell lysate View All» Quality Assurance: Evaluated by Western Blot in HEK293 cell lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected Plexin-D1 on 10 µg of HEK293 cell lysate. View All» Purification Method: Protein G View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9Y4D7 View All» Entrez Gene Number: NP_055918 View All» Gene Symbol:

• PLEXD1

• PLXND1
  View All» Alternate Names:
  • plexin D1

  • plexin-D1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein (Potential). TISSUE SPECIFICTY: Detected at low levels in heart, placenta, lung, skeletal muscle, kidney, thymus and liver. Detected at very low levels in brain, colon, spleen, small intestine and peripheral blood leukocytes. SEQUENCE SIMILARITIES: Belongs to the plexin family.Contains 3 IPT/TIG domains.Contains 1 Sema domain.SEQUENCE CAUTION: The sequence BAA31595.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened. View All» Product Name: Anti-Plexin-D1, clone 19C6.1 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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