货号：MAB10424

品牌：Merck Millipore

规格：100Ug

目录价：￥4192.00

市场价格：￥3563.20

会员价格：￥3353.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Plexin B3 Antibody, clone 17H10.1 | MAB10424 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: 206 kDa calculated View All» Immunogen: GST-tagged recombinant protein corresponding to human Plexin-B3. View All» Clone: 17H10.1 View All» Isotype: IgG2aκ View All» Background Information: Plexin-B3 is a member of the plexin-B family of semaphorin receptors. The plexin-B family of receptors may be especially important in axonal guidance during nervous system development. Plexin-B3 is thought to play an intricate and non-redundant role in this development. It is a specific receptor for Semaphorin-5A (Sema5A), whose activation by Sema5A mediates functional responses in Plexin-B3-expressing cells (either fibroblasts, epithelial and primary endothelial cells). Recently, Plexin-B3 has been described as a potent stimulator of neurite outgrowth, making it an intriguing research target for traits related to human brain development and cerebral connectivity. View All» Species Reactivity: Rat View All» Species Reactivity Note: Demonstrated to react with rat. Expected to react with human based on immunogen design. View All» Control: Normal rat brain tissue View All» Quality Assurance: Evaluated by Immunohistochemistry in normal rat brain tissue.Immunohistochemistry Analysis: 1:50 dilution of this antibody detected Plexin B3 in normal rat brain tissue. View All» Purification Method: Protein G View All» Presentation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9ULL4 View All» Entrez Gene Number: NP_001156729 View All» Gene Symbol:

• PLXN6

• PLEXB3

• PLEXR

• PLXNB3
  View All» Alternate Names:
  • plexin B3

  • plexin-B3

  • plexin 6
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry View All» Entrez Gene Summary: The protein encoded by this gene is a member of the plexin family. It functions as a receptor for semaphorin 5A, and plays a role in axon guidance, invasive growth and cell migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Receptor for SEMA5A. Plays a role in axon guidance, invasive growth and cell migration. SUBUNIT STRUCTURE: Binds MET and MST1R.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein TISSUE SPECIFICTY: Detected at very low levels in several fetal tissues. SEQUENCE SIMLARITIES: Belongs to the plexin family.Contains 4 IPT/TIG domains.Contains 1 Sema domain.SEQUENCE CAUTION: The sequence BAA86520.1 differs from that shown. Reason: Erroneous initiation. View All» Product Name: Anti-Plexin B3, clone 17H10.1 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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