货号：MAB1087

品牌：Merck Millipore

规格：100UL

目录价：￥4438.00

市场价格：￥3772.30

会员价格：￥3550.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Eosinophil Peroxidase Antibody, clone AHE-1 | MAB1087 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts specifically with human eosinophil peroxidase from eosinophils among peripheral blood cells. Eosinophil peroxidase is felt to play an important role in eosinophil function and perhaps endothelial injury in hypereosinophilic states. View All» Clone: AHE-1 View All» Isotype: IgG1 View All» Species Reactivity: Human View All» Application Notes: Final working dilutions must be determined by end user. View All» Presentation: Ascites fluid. View All» Storage Conditions: Maintain at -20°C in aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P11678 View All» Entrez Gene Number: NM_000502.2 View All» Gene Symbol:

• EPX

• EPO

• EPX-PEN

• EPER

• EPP

• EC 1.11.1.7 [Contains: Eosinophil peroxidase light chain

• Eosinophil peroxidase heavy chain].
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunocytochemistry View All» UniProt Summary: COFACTOR: Binds 1 calcium ion per heterodimer (By similarity). & Binds 1 heme B (iron-protoporphyrin IX) covalently through ester linkages to hydroxylated methyl groups formed auto- catalytically with hydrogen peroxide at the heme C-1 and C-5 positions. The ester linkage to Asp-232 was observed in 30% of the chains.SIZE: 715 amino acids; 81040 Da SUBUNIT: Tetramer of two light chains and two heavy chains.SUBCELLULAR LOCATION: Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils.DISEASE: SwissProt: P11678 # Defects in EPX are the cause of eosinophil peroxidase deficiency (EPD) [MIM:261500]. EPD is an autosomal recessive defect where anomalous eosinophils are characterized by nuclear hypersegmentation, hypogranulation, and negative peroxidase and phospholipid staining.SIMILARITY: SwissProt: P11678 ## Belongs to the peroxidase family. XPO subfamily. View All» Brand Family: Chemicon View All» Product Name: Anti-Eosinophil Peroxidase Antibody, clone AHE-1 | MAB1087 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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