Merck Millipore代理MAB11015 ANTI-PABPC4, CLONE 6E1.2

2025-06-27

货号:MAB11015

品牌:Merck Millipore

规格:EA

目录价:¥3784.00

市场价格:¥3216.40

会员价格:¥3027.20

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-polyclonalPC4 Antibody, clone 6E1.2 | MAB11015 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes human PABPC4 View All» Molecular Weight: ~70 kDa View All» Epitope: a.a. 416-427 View All» Immunogen: Immunogen was a KLH-conjugated, synthetic peptide corresonding to a.a. 416-427 of human PABPC4, between the RRM (RNA recognition motif) 4 and PABC domains. An additional C-terminal cysteine was added for coupling to KLH View All» Clone: clone 6E1.2 View All» Isotype: IgG1κ View All» Background Information: Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 (Poly(A) binding protein, cytoplasmic 4), also known as IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. PABPC4 may be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may be involved in the regulation of protein translation in platelets and megakaryocytes and may participate in the binding or stabilization of polyadenylates in platelet dense granules. View All» Species Reactivity: Human View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Protein G purfied View All» Presentation: Immunoaffinity purified rabbit IgG in 0.1 M Tris-Glycine (pH 7.4), 15 mM NaCl, 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt.For maximum recovery of product, centrifuge the vial prior to removing the cap. View All» UniProt Number: Q13310 View All» Entrez Gene Number: 8761 View All» Alternate Names:

  • poly(A) binding protein, cytoplasmic 4 (inducible form)

  • Inducible poly(A)-binding protein

  • Activated-platelet protein 1

    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary forregulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. View All» Brand Family: Upstate View All» Product Name: Anti-polyclonalPC4 Antibody, clone 6E1.2 | MAB11015 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»

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