货号：MAB1152

品牌：Merck Millipore

规格：500Ug

目录价：￥9841.00

市场价格：￥8364.85

会员价格：￥7872.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Interferon-γ Antibody, clone RMMG-1 | MAB1152 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with mouse Interferon gamma (IFNgamma). View All» Immunogen: Mouse Interferon gamma View All» Clone: RMMG-1 View All» Isotype: IgG1 View All» Species Reactivity: Mouse View All» Application Notes: Neutralizes mouse IFNgamma; binds to mouse IFNgamma with high affinity (KA= 10E9 M-1) Western blot (1:500) Immunoprecipitation Immunohistochemistry ELISA Optimal working dilutions must be determined by end user. View All» Presentation: Purified immunoglobulin. Liquid in PBS containing 0.1% bovine serum albumin. View All» Storage Conditions: Maintain frozen at -20°C or below for retention of full activity, for up to 12 months. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. View All» UniProt Number:

• P01579

• P01580
  View All» Gene Symbol: IFNG View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Immunoprecipitation

  • Western Blotting

  • Immunohistochemistry

  • Neutralizing
    View All» UniProt Summary: FUNCTION: SwissProt: P01579 # Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.SIZE: 166 amino acids; 19348 Da SUBUNIT: Homodimer.SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: Released primarily from activated T lymphocytes.PTM: Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.DISEASE: SwissProt: P01579 # In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.SIMILARITY: SwissProt: P01579 ## Belongs to the type II (or gamma) interferon family. View All» Brand Family: Chemicon View All» Product Name: Anti-Interferon-γ Antibody, clone RMMG-1 | MAB1152 View All» Concentration: 5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 500 µg View All» Format: Purified View All» Host: Rat View All»
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