货号：MAB1435

品牌：Merck Millipore

规格：100Ug

目录价：￥4592.00

市场价格：￥3903.20

会员价格：￥3673.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Macrophages/Monocytes Antibody, clone ED-1 | MAB1435 View All» Replaces: CBL1511; CBL260 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes a single chain glycoprotein of 90-100 kD that is expressed on the lysomal membrane of myeloid cells. Weak cell surface expression also occurs. The antigen is expressed by the majority of tissue macrophages and weakly by peripheral blood granulocytes. Studies have shown that the antigen has many characteristics in common with macrosialin in the mouse and CD68 in the human.Clone ED1, which recognises a CD68 like molecule in rat is an excellent marker of activated microglia. For pan microglial markers, staining both resting and activated microglia, use like CD11b (MAB1387Z and others) or iba-1 (MABN92). View All» Molecular Weight: 90-100 kD View All» Immunogen: Rat spleen cells View All» Clone: ED-1 View All» Isotype: IgG1 View All» Background Information: Monocytes are produced by the bone marrow from haematopoietic stem cell precursors called monoblasts. Monocytes circulate in the bloodstream for about one to three days and then typically move into tissues throughout the body. They consist of between 3 to 8 percent of the leukocytes in the blood. In the tissues monocytes mature into different types of macrophages at different anatomical locations.Macrophages are a type of white blood cell derived from monocytes that engulf invading antigenic molecules, viruses, and microorganisms and then display fragments of the antigen to activate helper T cells; ultimately stimulating the production of antibodies against the antigen. View All» Species Reactivity: Rat View All» Application Notes: Immunohistology on frozen sections at 1:50-1:300. Paraffin embedded tissue (Bouin fixation): 1:50-1:300 (requires pretreatment with trypsin or pronase). Flow cytometry at 1:100 - 1:200. Use 10 μL of this working dilution to label 10E6 cells. Radioimmunoassay Also suitable for Immunoprecipitation, and Western Blotting. Optimal working dilutions must be determined by end user. View All» Control: Macrophages, monocytes, lymphoid organs View All» Purification Method: Protein A purfied View All» Presentation: Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative. View All» Storage Conditions: Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:

• Flow Cytometry

• Immunocytochemistry

• Immunohistochemistry

• Immunoprecipitation

• Radioimmunoassay

• Western Blotting
  View All» Brand Family: Chemicon View All» Product Name: Anti-Macrophages/Monocytes Antibody, clone ED-1 | MAB1435 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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