货号：MAB1527

品牌：Merck Millipore

规格：300UL

目录价：￥6281.00

市场价格：￥5338.85

会员价格：￥5024.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Peripherin Antibody, clone 8G2 | MAB1527 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Peripherin. Strong staining on rat, mouse, human, pig and cow peripherin. Does not work on chicken or other more distantly related species, which may lack peripherin. View All» Molecular Weight: 57kDa View All» Immunogen: Electrophoretically pure trp-E-peripherin fusion protein [Dev. Brain Res. (1990). 57:235-248] containing all but the 4 N-terminal amino acids of rat peripherin. Fusion protein purified from bacterial inclusion bodies by DEAE-cellulose chromatography in 6M urea followed by preparative SDS-PAGE View All» Clone: 8G2 View All» Isotype: IgG View All» Background Information: Peripherin is a ~57kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems. Subsequently it was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration. View All» Species Reactivity:

• Bovine

• Human

• Mouse

• Pig

• Rat
  View All» Application Notes: Immunocytochemistry: 4% PFA fixed cells (5 minutes) or acetone is recommended. Immunohistochemisty: light PFA fixation is necessary as 8G2 is sensitive to heavy formalin fixation. Antigen recovery is enhanced with 0.1% triton in the block only. 1:25-1:200 Immunoblotting: The antibody is clean and specific for the expected 57kDa band on Western blots. Optimal working dilutions must be determined by end user. View All» Applications Not Recommended: Immunohistochemistry (Paraffin) View All» Control: Rat sensory neurons, rat spinal cord homogenate and peripheral nerve homogenate View All» Purification Method: Unpurified View All» Presentation: UnPurified mouse culture supernatant containing no preservatives. View All» Storage Conditions: Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P41219 View All» Entrez Gene Number: NM_006262.3 View All» Gene Symbol:
  • PRPH

  • PRPH1

  • Peripherin.

  • peripherin

  • NEF4
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. View All» UniProt Summary: FUNCTION: SwissProt: P41219 # Class-III neuronal intermediate filament protein.SIZE: 470 amino acids; 53651 Da SIMILARITY: SwissProt: P41219 ## Belongs to the intermediate filament family. View All» Brand Family: Chemicon View All» Product Name: Anti-Peripherin Antibody, clone 8G2 | MAB1527 View All» Concentration: Variable View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 300 μL View All» Format: Culture Supernatant View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-130005.htm
      © Merck Millipore代理MAB1527 Anti-Peripherin Antibody, clone 8G2;store at -20℃，产品报价联系微信jinshanbio