货号：MAB1567

品牌：Merck Millipore

规格：100Ug

目录价：￥6895.00

市场价格：￥5860.75

会员价格：￥5516.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Myelin Associated Glycoprotein Antibody, clone 513 | MAB1567 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Detects Myelin Associated Glycoprotein (MAG) in immunohistochemistry on frozen sections, immunocytochemistry and Western blot (under non-reducing conditions). MAB1567 is useful for myelinogenesis and multiple sclerosis studies. View All» Molecular Weight: 100 kDa View All» Immunogen: L2 epitope carrying glycoprotein extract of 1-2 day old chicken brain. View All» Clone: 513 View All» Isotype: IgG1 View All» Background Information: Myelin-associated glycoprotein (MAG),a member of the immunoglobulin superfamily, is a membrane glycoprotein of 100 kDa, and is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS. View All» Species Reactivity:

• Bovine

• Chicken

• Human

• Mouse

• Rat

• Frog
  View All» Species Reactivity Note: Human, rat, mouse, bovine, chicken, frog. View All» Application Notes: Western Blot: 20 μg/mL of a previous lot was used on western blot under non-reducing conditions only.{See Ellezam, 2003} Immunocytochemistry: 5-10 µg/mL of a previous lot was used, methanol fixation required.Optimal working dilutions must be determined by end user. View All» Control: Rat hippocampus tissue, rat brain lysate, PC12 cells. View All» Quality Assurance: Evaluated by immunohistochemistry on rat hippocampus.Immunohistochemistry(paraffin):Representative image from a previous lot.Mouse anti-Myelin Associated Glycoprotein [MAG] (Catalog Number MAB1567) localization of MAG in rat hippocampus. Photo courtesy of Dr. Robert Sloviter, University of Arizona. View All» Purification Method: Protein A purfied View All» Presentation: Purified mouse monoclonal IgG1 in buffer containing 10 mM potassium phosphate buffer, 50 mM NaCl, pH 7.5. Contains no preservative. View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt. View All» UniProt Number: P20916 View All» Entrez Gene Number: NM_002361.2 View All» Gene Symbol:
  • MAG

  • SIGLEC4A

  • SIGLEC-4A

  • Siglec-4a

  • S-MAG

  • GMA
    View All» Alternate Names: MAG View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P20916 # Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha2,3- linked sialic acid (By similarity).SIZE: 626 amino acids; 69069 Da SUBUNIT: Binds to RTN4R (By similarity).SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.SIMILARITY: SwissProt: P20916 ## Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. & Contains 4 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 Ig-like V-type (immunoglobulin-like) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Myelin Associated Glycoprotein Antibody, clone 513 | MAB1567 View All» Concentration: 1 .0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-130033.htm
      © Merck Millipore代理MAB1567 Anti-Myelin Associated Glycoprotein Antibody, clone 513;抗髓磷脂相关糖蛋白抗体，克隆513store at -20℃，产品报价联系微信jinshanbio