货号：MAB1572

品牌：Merck Millipore

规格：100UL

目录价：￥4131.00

市场价格：￥3511.35

会员价格：￥3304.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Parvalbumin Antibody | MAB1572 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Parvalbumin. The antibody will react with parvalbumin from brain and muscle. By immunoblot it recognizes a protein of 12 kDa. The antibody is directed against an epitope at the first Ca+2-binding site and specifically stains the Ca+2 -bound form of parvalbumin. View All» Molecular Weight: 12 kDa View All» Immunogen: Parvalbumin purified from frog muscle View All» Clone: PARV-19 View All» Isotype: IgG1 View All» Background Information: Parvalbumin is a calcium binding albumin protein. It has three EF hand motifs and is structurally related to calmodulin and troponin C. Parvalbumin is localised in fast-contracting muscles, where its levels are highest, and in the brain and some endocrine tissues. Parvalbumin is present in GABAergic interneurons in the nervous system, predominantly expressed by chandelier and basket cells in the cortex. View All» Species Reactivity:

• Bovine

• Canine

• Fish

• Feline

• Frog

• Goat

• Human

• Mouse

• Pig

• Rat

• Rabbit
  View All» Application Notes: Immunohistochemistry: A previous lot was used by indirect immunoperoxidase at 1:1,000-1:2,000 dilution. The antibody works on formalin fixed, paraffin embedded tissue sections of rat cerebellum from a previous lot. Fixation does not appear to affect MAB1572’s ability to detect parvalbumin.Immunocytochemistry: A previous lot of this antibody was used on cultured neurons.Optimal working dilutions must be determined by the end user. View All» Control: Brain tissue, Cultured neurons View All» Quality Assurance: Routinely evaluated by Western Blot on mouse brain lysate.Western Blot Analysis: 1:1000 dilution of this lot detected Parvalbumin on 10 μg of mouse brain lysate. View All» Purification Method: Unpurified View All» Presentation: Ascites mouse monoclonal IgG1 liquid with 0.1% sodium azide. View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt. View All» UniProt Number: P20472 View All» Entrez Gene Number: NM_002854.2 View All» Gene Symbol:
  • PVALB

  • MGC116759

  • parvalbumin

  • D22S749
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry (Paraffin)

    • Western Blotting
      View All» Entrez Gene Summary: The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. View All» UniProt Summary: FUNCTION: SwissProt: P20472 # In muscle, the calcium-binding protein parvalbumin is thought to be involved in muscle relaxation.SIZE: 110 amino acids; 12059 Da SIMILARITY: SwissProt: P20472 ## Belongs to the parvalbumin family. & Contains 2 EF-hand domains. MISCELLANEOUS: This protein binds two calcium ions. View All» Brand Family: Chemicon View All» Product Name: Anti-Parvalbumin Antibody | MAB1572 View All» Concentration: Variable View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Neurons, muscle View All» Format: Ascites View All» Host: Mouse View All»
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