货号：MAB1576

品牌：Merck Millipore

规格：100UL

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2 | MAB1576 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: m4 muscarinic acetylcholine receptor. No reactivity with the other subtypes. View All» Immunogen: m4 receptor i3 loop (human), fused to GST View All» Clone: 17F10.2 View All» Isotype: IgG1 View All» Species Reactivity:

• Mouse

• Monkey

• Rat
  View All» Application Notes: Immunohistochemistry (rat and monkey) Western blot (rat, mouse, human): ECL 4-10 μg/mL Immunoprecipitation (rat) Optimal working dilutions must be determined by the end user. View All» Presentation: Liquid in 0.02M Phosphate buffer, 0.25 M NaCl, pH=7.6 with 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months. View All» UniProt Number: P08173 View All» Entrez Gene Number: NM_000741.2 View All» Gene Symbol:
  • CHRM4

  • HM4
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. View All» UniProt Summary: FUNCTION: SwissProt: P08173 # The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.SIZE: 479 amino acids; 53049 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.SIMILARITY: SwissProt: P08173 ## Belongs to the G-protein coupled receptor 1 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2 | MAB1576 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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