货号：MAB1613

品牌：Merck Millipore

规格：100Ug

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Kinesin Antibody, heavy chain, non-neuronal KHC, clone H1 | MAB1613 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with the major form of heavy chain of non-neuronal KHC near the N-terminus. View All» Epitope: heavy chain, non-neuronal KHC View All» Immunogen: Bovine brain kinesin. View All» Clone: H1 View All» Isotype: IgG1 View All» Species Reactivity:

• Bovine

• Human

• Rat
  View All» Application Notes: Immunohistochemistry on paraformaldehyde fixed tissue. Also works for EM. Immunocytochemistry: paraformaldehyde fixed cells; 5-10' RT, freshly made 4% PFA; permeabilize with 0.1-.2% triton X-100 in 3% normal serum blocking buffer Immunoblotting: recognizes 124kDa KHC from non-neuronal samples. Immunoprecipitation Inhibition of kinesin mediated transport EIA/RIA Optimal working dilutions must be determined by the end user. View All» Presentation: Liquid in 0.02 M Phosphate buffer, 0.25 M NaCl.pH 7.6 with 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months. View All» UniProt Number: P33176 View All» Entrez Gene Number: NM_004521.1 View All» Gene Symbol:
  • KIF5B

  • UKHC

  • KINH

  • KNS1

  • KNS
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Immunoprecipitation

    • Radioimmunoassay

    • Western Blotting

    • Immunocytochemistry

    • Immunohistochemistry

    • Affects Function
      View All» UniProt Summary: FUNCTION: SwissProt: P33176 # Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity).SIZE: 963 amino acids; 109685 Da SUBUNIT: Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 (By similarity). Interacts with SYBU.SUBCELLULAR LOCATION: Note=Uniformly distributed between soma and neurites in hippocampal neurons (By similarity).DOMAIN: SwissProt: P33176 Composed of three structural domains: a large globular N- terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.SIMILARITY: Belongs to the kinesin-like protein family. Kinesin subfamily. & Contains 1 kinesin-motor domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Kinesin Antibody, heavy chain, non-neuronal KHC, clone H1 | MAB1613 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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