货号：MAB1668

品牌：Merck Millipore

规格：100Ug

目录价：￥5359.00

市场价格：￥4555.15

会员价格：￥4287.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Phospholipase A2 Antibody, clone CH-7 | MAB1668 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Antibody reacts with cytosolic form of PLA2. Antibody will also react with beta isoform. Epitope has been localized within the first 216 aa of the N-terminal Ca++ binding domain of cPLA2 View All» Immunogen: Recombinant cPLA2 expressed from the human cPLA2 gene. View All» Modifications: Phosphorylation View All» Clone: CH-7 View All» Isotype: IgG2b View All» Species Reactivity: Recombinant Human Protein View All» Application Notes: Immunoblot: 1:500-1:1000; antibody recognizes all isoforms, the cPLA. Alpha (85kDa) typically migrates as 100-110kDa on reducing westerns; beta migrates as 114kDa; antibody will also recognize the sPLA at approximately 14-20kDa. ELISA Optimal working dilutions must be determined by the end user. View All» Presentation: In 20 mM sodium phosphate, 250 mM sodium chloride, 0.1% sodium azide, pH. 7.6 View All» Storage Conditions: Maintain at 2-8°C. View All» UniProt Number: P04054 View All» Entrez Gene Number: NM_000928.2 View All» Gene Symbol:

• PLA2G1B

• MGC119834

• PPLA2

• PLA2

• PLA2A

• MGC119835

• EC 3.1.1.4
  View All» Alternate Names: PLA2 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Western Blotting
    View All» Entrez Gene Summary: Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 [PubMed 3028739]) .[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: P04054 # PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides.COFACTOR: Binds 1 calcium ion per subunit (By similarity).SIZE: 148 amino acids; 16360 Da SUBCELLULAR LOCATION: Secreted.SIMILARITY:SwissProt: P04054 ## Belongs to the phospholipase A2 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Phospholipase A2 Antibody, clone CH-7 | MAB1668 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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