货号：MAB1693

品牌：Merck Millipore

规格：

目录价：￥2960.00

市场价格：￥2516.00

会员价格：￥2368.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Troponin T Antibody, clone 2G3 | MAB1693 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Human cardiac Troponin T No cross reactivity with human skeletal Troponin T View All» Immunogen: Human cardiac Troponin T View All» Clone: 2G3 View All» Isotype: IgG2b View All» Species Reactivity: Human View All» Application Notes: ELISA at 1:7,000,000 Immunoaffinity purification Western blot Optimal working dilutions must be determined by the end user. View All» Presentation: Purified immunoglobulin from Protein A Sepharose™ 4B column chromatography. Purity >95% by gel electrophoresis. Liquid in PBS pH 7.4 containing 0.1% sodium azide as a preservative View All» Storage Conditions: Maintain refrigerated at +2-8°C for up to 6 months after date of receipt. View All» UniProt Number: P19429 View All» Entrez Gene Number: NM_000363.4 View All» Gene Symbol:

• TNNI3

• TNNC1

• CMH7

• MGC116817

• cTnI
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Western Blotting
    View All» Entrez Gene Summary: Troponin I (TnI) is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle; see also TNNI1 (MIM 191042). The others are troponin T (TnT; see MIM 191041) and troponin C (TnC; see MIM 191040).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: P19429 # Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.SIZE: 210 amino acids; 24008 Da SUBUNIT: Binds to actin and tropomyosin. Interacts with TRIM63.DISEASE: SwissProt: P19429 # Defects in TNNI3 are the cause of familial hypertrophic cardiomyopathy type 7 (CMH7) [MIM:191044]; also designated FHC or HCM. Familial hypertrophic cardiomyopathy [MIM:192600] is a heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The prevalence of the disease in the general population is 0.2%. FHC is clinically heterogeneous, with inter- and intrafamilial variations ranging from benign to malignant forms with a high risk of cardiac failure and sudden cardiac death. & Defects in TNNI3 are the cause of familial restrictive cardiomyopathy (RCM) [MIM:115210]. RCM is an heart muscle disorder characterized by impaired filling of the ventricles with reduced volume in the presence of normal or near normal wall thickness and systolic function. The disease may be associated with systemic disease but is most often idiopathic.SIMILARITY: SwissProt: P19429 ## Belongs to the troponin I family. View All» Brand Family: Chemicon View All» Product Name: Anti-Troponin T Antibody, clone 2G3 | MAB1693 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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