货号：05-1925

品牌：Merck Millipore

规格：EA

目录价：￥3108.00

市场价格：￥2641.80

会员价格：￥2486.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Lactoylglutathione lyase, clone Glo1a View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Lactoylglutathione lyase. View All» Molecular Weight: ~ 21 kDa View All» Epitope: Unknown View All» Immunogen: GST-tagged recombinant protein corresponding to human Lactoylglutathione lyase. View All» Clone: Glo1a View All» Isotype: IgG1κ View All» Background Information: Lactoylglutathione lyase is a detoxifying enzyme involved in the glyoxalase system and is responsible for the catalysis of methylglyoxal and lactate. Lactoylglutathione lyase is also referred to as Glyoxalase I. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with human. View All» Application Notes: Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC. (Case Western Reserve University) View All» Control: HeLa cell lysate View All» Quality Assurance: Evaluated by Western Blot in HeLa cell lysate.Western Blot Analysis: 0.1 µg/ml of this antibody detected Lactoylglutathione lyase on 10 µg of HeLa cell lysate. View All» Purification Method: Protein G purfied View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q04760 View All» Entrez Gene Number: NP_006699.2 View All» Gene Symbol:

• GLO1

• Aldoketomutase

• GLOD1

• GLYI

• Methylglyoxalase
  View All» Alternate Names:
  • Glx I

  • Ketone-aldehyde mutase

  • S-D-lactoylglutathione methylglyoxal lyase

  • glyoxalase I

  • glyoxalase domain containing 1

  • lactoyl glutathione lyase
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunocytochemistry
      View All» Entrez Gene Summary: The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.CATALYTIC ACTIVITY: (R)-S-lactoylglutathione = glutathione + methylglyoxal.COFACTOR: Binds 1 zinc ion per subunit.PATHWAY: Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.SUBUNIT STRUCTURE: Homodimer.POLYMORPHISM: Exists in three separable isoforms which originate from two alleles in the genome. These correspond to two homodimers and one heterodimer composed of two subunits showing different electrophoretic properties.SEQUENCE SIMILARITIES: Belongs to the glyoxalase I family. View All» Product Name: Anti-Lactoylglutathione lyase, clone Glo1a View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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