货号：07-2190

品牌：Merck Millipore

规格：

目录价：￥3346.00

市场价格：￥2844.10

会员价格：￥2676.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-CAPZIP (Ser108) View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes CAPZIP phosphorylated at Ser108. View All» Molecular Weight: ~75 kDa Observed View All» Epitope: Phosphorylated Ser108 View All» Immunogen: KLH-conjugated linear peptide corresponding to human CAPZIP phosphorylated at Ser108. View All» Modifications: Phosphorylation View All» Background Information: CAPZIP (CapZ-interacting protein) is highly expressed in immune cells and muscle and uniquely interacts with CapZ, an F-actin capping protein, in splenocytes. Phosphorylation of CAPZIP is thought to regulate CapZ ability to remodel actin filament assembly. CAPZIP may also contain a CPI (capping protein interaction) motif that seems to restrict capping protein to a low-affinity, filament-binding conformation. View All» Species Reactivity:

• Human

• Rat

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with human. Predicted to react with rat and mouse based on 100% sequence homology. View All» Control: Untreated and Anisomycin treated Jurkat cell lysate. View All» Quality Assurance: Evaluated by Western Blot in untreated and Anisomycin treated Jurkat cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected CAPZIP on 10 µg of Anisomycin treated Jurkat cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt.. View All» UniProt Number: Q6JBY9 View All» Entrez Gene Number: NP_443094 View All» Gene Symbol:
  • CAPZIP

  • MK2S4

  • RCSD1
    View All» Alternate Names:
    • RCSD domain containing 1

    • capZ-interacting protein

    • Protein kinase substrate CapZIP

    • protein kinase substrate MK2S4

    • RCSD domain-containing protein 1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: Stress-induced phosphorylation of CAPZIP may regulate the ability of F-actin-capping protein to remodel actin filament assembly.SUBUNIT STRUCTURE: Interacts with CAPZA2 and CAPZB.TISSUE SPECIFICITY: Highly expressed in skeletal muscle and more weakly in cardiac muscle. Also expressed in several lymphoid organs, including spleen, thymus, peripheral blood leukocytes, lymph node and bone marrow.POST-TRANSLATIONAL MODIFICATION: Dephosphorylation results in its dissociation from CAPZA2.SEQUENCE SIMILARITIES: Contains 1 RCSD domain.SEQUENCE CAUTION: The sequence CAB70910.1 differs from that shown. Reason: Erroneous initiation. View All» Product Name: Anti-phospho-CAPZIP (Ser108) View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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