货号：MAB2608

品牌：Merck Millipore

规格：

目录价：￥3978.00

市场价格：￥3381.30

会员价格：￥3182.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Sidekick-2 Antibody, clone CS22 | MAB2608 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~237 kDa observed View All» Immunogen: Histidine-tagged recombinant protein corresponding to chicken Sidekick-2. View All» Clone: CS22 View All» Isotype: IgG1κ View All» Background Information: Protein sidekick-2 (Sdk-2) is a single-pass type-I membrane protein containing thirteen fibronectin type-III domains and six Ig-like C2-type domains. Sdk-2 is a homophilic, synaptic adhesion molecule that functions to upregulate retinal lamina-specific connectivity. Expression of Sdk-2 is observed in non-overlapping retinal neuron subsets and is concentrated at synapses that connect Sdk-expressing partners, both postsynaptic and presynaptic. View All» Species Reactivity:

• Human

• Chicken
  View All» Species Reactivity Note: Demonstrated to react with human. Predicted to react with chicken based on 100% sequence homology. View All» Application Notes: Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (Yamagata, M., et al. (2010). The Journal of Neuroscience. 30(10):3579-3588.) View All» Control: Y79 cell lysate View All» Quality Assurance: Evaluated by Western Blot in Y79 cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected Sidekick-2 in 10 µg of Y79 cell lysate. View All» Purification Method: Protein G Purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8AV57 View All» Entrez Gene Number: NP_989869 View All» Gene Symbol: SDK2 View All» Alternate Names:
  • sidekick homolog 2 (chicken)

  • Drosophila sidekick-like

  • protein sidekick-2

  • chicken sidekick 2-like
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» UniProt Summary: FUNCTION: Synaptic adhesion molecule that promotes lamina-specific connectivity in the retina. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (Potential). Cell junction › synapse (Potential). TISSUE SPECIFICTY: Expressed by non-overlapping subsets of retinal neurons. Concentrated at synapses. SEQUENCE SIMILARITIES: Contains 13 fibronectin type-III domains.Contains 6 Ig-like C2-type (immunoglobulin-like) domains.Sequence caution The sequence AAN15076.1 differs from that shown. Reason: Erroneous initiation. View All» Product Name: Anti-Sidekick-2, clone CS22 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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