货号：MAB2626

品牌：Merck Millipore

规格：200UL

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Endosialin Antibody, clone B1/35 | MAB2626 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~175 kDa observed View All» Immunogen: Diploid human fibroblasts View All» Clone: B1/35 View All» Isotype: IgG1κ View All» Background Information: Endosialin is a glycoprotein on the cell surface of vascular endothelial cells in a broad range of human cancers. Endosialin is thought to be highly expressed at the points of active tissue remodeling and neovascularisation which may imply that endosialin is key in tumor growth, angiogenesis and metastasis. Endosialin has structural similarity to CD93, which involves a C-type lectin-like domain, EGF-like repeats and a glycosylated mucin-like domain. This similarity may also suggest that endosialin plays a role in innate immunity and inflammation. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with human. View All» Application Notes: Flow Cytometry Analysis: A previous lot was used by an independent laboratory in FC to detect Endosialin in rheumatoid fibroblasts (MacFadyen, J. et al. (2005). FEBS. 579(12):2569-2575).Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP on AG1523 human fibroblasts (MacFadyen, J. et al. (2005). FEBS. 579(12):2569-2575).Immunofluorescent Analysis: A previous lot was used by an independent laboratory in IF to detect Endosialin in human rheumatoid synovium, tonsil, salivary gland and normal breast tissues (MacFadyen, J. et al. (2005). FEBS. 579(12):2569-2575). View All» Control: AG1523 cell lysate View All» Quality Assurance: Evaluated by Western Blot in AG1523 cell lysate.Western Blot Analysis: A 1:2,500 dilution of this antibody detected Endosialin in 10 µg of AG1523 cell lysate. View All» Purification Method: Protein G Purified View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9HCU0 View All» Entrez Gene Number: NP_065137 View All» Gene Symbol:

• CD248

• TEM1

• CD164L1
  View All» Alternate Names:
  • CD248 molecule, endosialin

  • CD164 sialomucin-like 1

  • endosialin

  • CD248 antigen, endosialin

  • Tumor endothelial marker 1

  • CD248 antigen
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunoprecipitation

    • Immunofluorescence

    • Flow Cytometry
      View All» UniProt Summary: FUNCTION: May play a role in tumor angiogenesis. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein Probable. TISSUE SPECIFICTY: Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts. PTM: O-glycosylated with sialylated oligosaccharides. May be N-glycosylated. SEQUENCE SIMILARITIES: Contains 1 C-type lectin domain.Contains 1 EGF-like domain.Contains 1 Sushi (CCP/SCR) domain. View All» Product Name: Anti-Endosialin, clone B1/35 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 200 µL View All» Target / Localization: pericyte marker of embryonic and tumor neovascularization View All» Format: Purified View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-130749.htm
      © Merck Millipore代理MAB2626 Anti-Endosialin Antibody, clone B1/35;store at +2℃ to +8℃，产品报价联系微信jinshanbio