货号：MAB312R

品牌：Merck Millipore

规格：100Ug

目录价：￥6588.00

市场价格：￥5599.80

会员价格：￥5270.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-A2B5 Antibody, clone A2B5-105 | MAB312R View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes an epitope common to silaogangliosides and sulfatides from the plasma membranes of neurons, and neuroendocrine and glial cells. Anti-A2B5 has been used to specifically stain: Neurofibrillary tangles in the post-mortem brain tissue of patients with a confirmed diagnosis of Alzheimer's disease (Majocha et al., 1989) Neurons of chicken retina, brain, spinal cord, and dorsal root ganglia (Schnitzer & Schachner, 1982; Eisenbarth et al., 1979). Rat striatal nerve terminals [synaptosomes (Wolf & Kapatos, 1989)]. Neuroblastoma cells in man (Oppedal et al., 1989; Coakham et al., 1985). Rat insulinoma cells and pancreatic islets cells (Shimizu et al., 1983; Bartholomeusz et al., 1989). Human and rat thymic epithelial cells (Haynes et al., 1988). Cells involved in gliogenesis (Bottenstein et al., 1988; Suzumura & Slerberg, 1989). Oligodendrocytes and astrocytes, type II (Dubois-Dalcq et al., 1990). View All» Immunogen: Embryonic chicken retinal cells View All» Clone: A2B5-105 View All» Isotype: IgM View All» Background Information: A2B5 is a cell surface ganglioside epitope expressed in developing thymic epithelial cells, oligodendrocyte progenitors and neuroendocrine cells. The A2B5 antigen is present in type 2 astrocytes but absent in type 1 astrocytes, allowing for the differentiation of these different types of cells. A2B5 antibody has been used in flow cytometry and immunohistochemistry experiments to stain type II astrocytes, cells involved in gliogenesis and cells committed to the oligodendrocyte lineage. View All» Species Reactivity: Mammals View All» Application Notes: Immunocytochemistry: 5-10 μg/mL Immunohistochemistry: 5-10 μg/mL (Levison & McCarthy, 1989) Complement-mediated cytotoxicity (Eisenbarth et al., 1979) Flow cytometry: live cells {Maric, D. et al. (2000) Cerebral Cortex 10:729-747}. Optimal working dilutions must be determined by end user. View All» Control: Type II astrocytes, human neural progenitors View All» Purification Method: Ammonium sulfate precipitation View All» Presentation: Liquid. Buffer = PBS, pH 7.1 with 2 mg/mL BSA. View All» Storage Conditions: Maintain the lyophilizate frozen at -20°C. Store the reconstituted antibody solution at -20°C for 12 months in undiluted aliquots. View All» Gene Symbol: A2B5 View All» Alternate Names: Neuron Cell Surface Antigen View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:

• Flow Cytometry

• Immunocytochemistry

• Immunofluorescence

• Immunohistochemistry
  View All» Brand Family: Chemicon View All» Product Name: Anti-A2B5 Antibody, clone A2B5-105 | MAB312R View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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