货号：MAB324

品牌：Merck Millipore

规格：100Ug

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Neuron Specific Enolase Antibody, clone 5E2 | MAB324 View All» Replaces: CBL220 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Human gamma neuron specific enolase. Recognizes a 45kD band corresponding to gamma NSE on immunoblots of human brain extracts. View All» Immunogen: Neuron-specific enolase from human brain. View All» Clone: 5E2 View All» Isotype: IgG2a View All» Species Reactivity: Human View All» Application Notes: Immunoblotting ELISA Immunohistochemistry. May be used on formalin-fixed, paraffin embedded sections. Optimal working dilutions must be determined by end user. View All» Presentation: Liquid in PBS pH 7.4 containing 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8 °C for up to 12 months under sterile conditions. View All» UniProt Number: P09104 View All» Entrez Gene Number: NM_001975.2 View All» Gene Symbol:

• ENO2

• NSE

• Gamma-enolase

• EC 4.2.1.11
  View All» Alternate Names: NSE View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Western Blotting

  • Immunocytochemistry

  • Immunohistochemistry (Paraffin)
    View All» Entrez Gene Summary: This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. View All» UniProt Summary: FUNCTION: SwissProt: P09104 # Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).COFACTOR: Magnesium. Required for catalysis and for stabilizing the dimer.SIZE: 434 amino acids; 47269 Da SUBUNIT: Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific.SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form (By similarity).TISSUE SPECIFICITY: The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.DEVELOPMENTAL STAGE: During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.SIMILARITY: SwissProt: P09104 ## Belongs to the enolase family. View All» Brand Family: Chemicon View All» Product Name: Anti-Neuron Specific Enolase Antibody, clone 5E2 | MAB324 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Target / Localization: Cytoplasmic View All» Format: Purified View All» Host: Mouse View All»
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