货号：01-172

品牌：Merck Millipore

规格：

目录价：￥3955.00

市场价格：￥3361.75

会员价格：￥3164.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: IFNγ View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 100 µg View All» Key Applications: Cell Culture View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» UniProt Summary: FUNCTION: SwissProt: P01579 # Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.SIZE: 166 amino acids; 19348 Da SUBUNIT: Homodimer.SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: Released primarily from activated T lymphocytes.PTM: Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.DISEASE: SwissProt: P01579 # In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.SIMILARITY: SwissProt: P01579 ## Belongs to the type II (or gamma) interferon family. View All» Species: Human View All» Brand Family: Upstate View All» Source: Recombinant Human Interferon-gamma View All» Presentation: Lyophilized from PBS, pH 7.4 View All» Gene Symbol:

• IFNG

• IFN-gamma

• IFI

• IFG
  View All» Product Name: IFNγ View All» Quality Assurance: Routinely evaluated in a biological activity assay. View All» Physical Form: Lyophilized View All» UniProt Number: P01579 View All» Entrez Gene Number: NM_000619.2 View All» Purification Method: Sterilized through a 0.2 micron membrane filter View All»
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