货号：MAB3291

品牌：Merck Millipore

规格：100Ug

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-H-Ras Antibody, clone 7D7.2 | MAB3291 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes H-Ras (the oncogene of Harvey murine sarcoma virus). Approximate molecular weight of 21 kDa. View All» Immunogen: Full-length recombinant human H-Ras - GST fusion protein View All» Clone: 7D7.2 View All» Isotype: IgG2b View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Western blot ELISA Optimal working dilutions must be determined by end user. View All» Presentation: 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, 0.1% sodium azide View All» Storage Conditions: Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months. WARNING: The monoclonal reagent solution contains 0.1% sodium azide as a preservative. Due to potential hazards arising from the build up of this material in pipes, spent reagent should be disposed of with liberal volumes of water. View All» UniProt Number: P01112 View All» Entrez Gene Number:
  • NM_005343.2

  • NM_176795.2
    View All» Gene Symbol:
    • HRAS

    • c-bas/has

    • H-Ras-1

    • RASH1

    • Ha-Ras

    • K-ras

    • N-ras

    • p21ras

    • c-H-ras

    • H-RasIDX

    • CTLO

    • HRAS1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • ELISA

      • Western Blotting
        View All» UniProt Summary: FUNCTION: SwissProt: P01112 # Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.SIZE: 189 amino acids; 21298 Da SUBUNIT: In its GTP-bound form interacts with PLCE1. Interacts with TBC1D10C. Interacts with RGL3 (By similarity).SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor. Note=Shuttles between the plasma membrane and the Golgi apparatus.PTM: Palmitoylated by the ZDHHC9-GOLGA7 complex. A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi.DISEASE: SwissProt: P01112 # Defects in HRAS are the cause of Costello syndrome [MIM:218040]; also known as faciocutaneoskeletal syndrome. Costello syndrome is a rare condition characterized by prenatally increased growth, postnatal growth deficiency, mental retardation, distinctive facial appearance, cardiovascular abnormalities (typically pulmonic stenosis, hypertrophic cardiomyopathy and/or atrial tachycardia), tumor predisposition, skin and musculoskeletal abnormalities. & Mutations which change positions 12, 13 or 61 activate the potential of c-ras to transform cultured cells and are implicated in a variety of human tumors. & Defects in HRAS are a cause of bladder cancer [MIM:109800]. & Defects in HRAS are also the cause of oral squamous cell carcinoma (OSCC).SIMILARITY: SwissProt: P01112 ## Belongs to the small GTPase superfamily. Ras family. View All» Brand Family: Chemicon View All» Product Name: Anti-H-Ras Antibody, clone 7D7.2 | MAB3291 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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