货号：MAB3304

品牌：Merck Millipore

规格：100Ug

目录价：￥4755.00

市场价格：￥4041.75

会员价格：￥3804.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Collagen Type IX Antibody, clone 23-5D1 | MAB3304 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: The antibody specifically reacts with the hCL(IX). This is a purified mouse monoclonal antibody to a synthesized oligopeptide sequence (GRAPTDQHIKQVC) comprising three amino acids of the COL2 domain and 10 amino acids in the NC2 domain of the human a1 (IX) collagen chain. SPECIES REACTIVITY: MAB3304 cross-reacts with bovine, mouse, rabbit and lapin CL(IX). View All» Clone: 23-5D1 View All» Isotype: IgG2aκ View All» Species Reactivity:

• Human

• Rat

• Rabbit
  View All» Application Notes: Immunoblotting: 120 kDa ElA View All» Presentation: Liquid in 0.1M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine serum albumin. View All» Storage Conditions: Maintain frozen at -20°C in undiluted aliquots for up to 12 months. View All» UniProt Number: P20849 View All» Entrez Gene Number:
  • NM_001851.3

  • NM_078485.2
    View All» Gene Symbol:
    • COL9A1

    • DJ149L1.1.2

    • FLJ40263

    • MED
      View All» Sales Restrictions: This product is not available for sale in Japan. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • ELISA

      • Western Blotting
        View All» Entrez Gene Summary: This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene may be associated with multiple epiphyseal dysplasia. Two transcript variants have been identified for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P20849 # Structural component of hyaline cartilage and vitreous of the eye.SIZE: 921 amino acids; 91855 Da SUBUNIT: Heterotrimer of an alpha 1(IX), an alpha 2(IX) and an alpha 3(IX) chain.SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix (By similarity).DOMAIN: SwissProt: P20849 Each subunit is composed of three triple-helical domains interspersed with non-collagenous domains. The globular domain at the N-terminus of type IX collagen molecules represents the NC4 domain which may participate in electrostatic interactions with polyanionic glycosaminoglycans in cartilage.PTM: Covalently linked to the telopeptides of type II collagen by lysine-derived cross-links. & Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.DISEASE:SwissProt: P20849 # Defects in COL9A1 are a cause of COL9A1-related multiple epiphyseal dysplasia (COL9A1-MED) [MIM:120210].SIMILARITY: Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. & Contains 1 TSP N-terminal (TSPN) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Collagen Type IX Antibody, clone 23-5D1 | MAB3304 View All» Concentration: 2 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Target / Localization: Proliferating chondrocytes of the cartilage element View All» Format: Purified View All» Host: Mouse View All»
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