货号：MAB3315

品牌：Merck Millipore

规格：100Ug

目录价：￥4967.00

市场价格：￥4221.95

会员价格：￥3973.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MMP-7 Antibody, clone 141-7B2 | MAB3315 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: The antibody specifically reacts with precursor form of human MMP-7. Does not cross-react with the active forms of human MMP-7 and human MMP-1, 2, 3, 8, 9 and 13. View All» Immunogen: Rectal carcinoma (SW837) cells. View All» Clone: 141-7B2 View All» Isotype: IgG1κ View All» Species Reactivity: Human View All» Application Notes: Immunoblotting: 10 μg/mL Molecular weight band around 30kDa. Immunohistochemistry on paraffin-embedded tissue sections: 4-20 μg/mL EIA Optimal working dilutions must be determined by end user. View All» Presentation: Purified immunoglobulin. Liquid in 0.1 M sodium phosphate buffer, pH 7.0 containing 2% protease-free bovine serum albumin. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P09237 View All» Entrez Gene Number: NM_002423.3 View All» Gene Symbol:

• MMP7

• MPSL1

• matrin

• MMP-7

• PUMP-1

• Matrin

• PUMP1

• EC 3.4.24.23
  View All» Alternate Names: Matrilysin View All» Sales Restrictions: This product is not available for sale in Japan. View All» Usage Statement:
  • Manufactured by Daiichi Fine Chemical Co., Ltd

  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    View All» Key Applications:
    • ELISA

    • Western Blotting

    • Immunohistochemistry (Paraffin)
      View All» Entrez Gene Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. View All» UniProt Summary: FUNCTION: SwissProt: P09237 # Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.COFACTOR: Binds 2 calcium ions per subunit. & Binds 2 zinc ions per subunit.SIZE: 267 amino acids; 29677 Da DOMAIN: SwissProt: P09237 The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.SIMILARITY: Belongs to the peptidase M10A family. View All» Brand Family: Chemicon View All» Product Name: Anti-MMP-7 Antibody, clone 141-7B2 | MAB3315 View All» Concentration: 2 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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