货号：MAB3322

品牌：Merck Millipore

规格：

目录价：￥4013.00

市场价格：￥3411.05

会员价格：￥3210.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MMP-7 Antibody, active form, a.a. 78-82, clone 176-5F12 | MAB3322 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: The antibody specifically reacts with the human MMP-7. This is a purified mouse monoclonal antibody to a peptide (YSLFP, R78-82) of human matrix metalloproteinase 7 (human MMP-7, matrilysin) SPECIES REACTIVITY: MAB3322 does not cross-react with the precursor form of human MMP-7 and human MMP-1, 2, 3, 8, 9 and 13. View All» Epitope: active form, a.a. 78-82 View All» Clone: 176-5F12 View All» Isotype: IgG1κ View All» Species Reactivity: Human View All» Application Notes: Immunoblotting: reacts with active form of hMMP-7 (~19 kDa) but not the proform hMMP-7 (~28kDa); will not react with CC1059 in westerns blots. EIA View All» Presentation: Liquid in 0.1 M sodium phosphate buffer, pH 7.0 containing 2% protease free bovine serum albumin. View All» Storage Conditions: Maintain frozen at -20°C in undiluted aliquots for up to 12 months. View All» UniProt Number: P09237 View All» Entrez Gene Number: NM_002423.3 View All» Gene Symbol:

• MMP7

• MPSL1

• matrin

• MMP-7

• PUMP-1

• Matrin

• PUMP1

• EC 3.4.24.23
  View All» Alternate Names: Matrilysin View All» Sales Restrictions: This product is not available for sale in Japan. View All» Usage Statement:
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

  • Manufactured by Daiichi Fine Chemical Co., Ltd
    View All» Key Applications:
    • ELISA

    • Western Blotting
      View All» Entrez Gene Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. View All» UniProt Summary: FUNCTION: SwissProt: P09237 # Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.COFACTOR: Binds 2 calcium ions per subunit. & Binds 2 zinc ions per subunit.SIZE: 267 amino acids; 29677 Da DOMAIN: SwissProt: P09237 The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.SIMILARITY: Belongs to the peptidase M10A family. View All» Brand Family: Chemicon View All» Product Name: Anti-MMP-7 Antibody, active form, a.a. 78-82, clone 176-5F12 | MAB3322 View All» Concentration: 2 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-131006.htm
      © Merck Millipore代理MAB3322 Ms X Hu MMP-7, clone 176-5F12，产品报价联系微信jinshanbio