货号：MAB3402

品牌：Merck Millipore

规格：40Ug

目录价：￥5666.00

市场价格：￥4816.10

会员价格：￥4532.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5 | MAB3402 View All» Replaces: CBL411 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: The antibody reacts with GFAP from human, pig, chicken and rat. In tissue sections this antibody stains astrocytes and Bergman glia cells (Debus, E., 1983). View All» Molecular Weight: 50 kDa View All» Immunogen: Purified glial filament (Debus, E., 1983). View All» Clone: GA5 View All» Isotype: IgG1 View All» Background Information: Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system. View All» Species Reactivity:

• Human

• Rat

• Mouse

• Pig

• Chicken

• Bovine

• Rabbit
  View All» Species Reactivity Note: Human, mouse, and rat. Expected to cross-react with porcine, chicken, bovine, and rabbit. View All» Application Notes: Immunocytochemistry: 5 μg/mL of a previous lot was used.Immunohistochemistry: 5 µg/mL Immunoblotting: Recognizes a 51kDa protein in reducing westerns of total brain lysates. Optimal working dilutions must be determined by end user. View All» Control: Mouse brain tissue, Astrocyte culture. View All» Quality Assurance: Routinely evaluated by Western Blot on Mouse brain lysate.Western Blot Analysis: 1:1000 dilution of this lot detected Glial Fibrillary Acidic Protein on 10 μg of Mouse Brain lysate. View All» Purification Method: Protein A purfied View All» Presentation: Purified mouse monoclonal IgG1 in buffer containing 0.02 M phosphate buffer, 0.25 M NaCl with 0.1% sodium azide, pH 7.6. View All» Storage Conditions: Store the reconstituted antibody at 2-8°C for up to 6 months after date of receipt. DO NOT FREEZE. View All» UniProt Number: P14136 View All» Entrez Gene Number: NM_002055.2 View All» Gene Symbol:
  • GFAP

  • FLJ45472
    View All» Alternate Names: GFAP View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Immunohistochemistry (Paraffin)

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant has been described, but its full length sequence has not been determined. View All» UniProt Summary: FUNCTION: SwissProt: P14136 # GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.SIZE: 432 amino acids; 49880 Da SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander disease [MIM:203450]. Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death usually within the first decade. Infants with Alexander disease develop a leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation. Patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity, and a more slowly progressive course.SIMILARITY: SwissProt: P14136 ## Belongs to the intermediate filament family. View All» Brand Family: Chemicon View All» Product Name: Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5 | MAB3402 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 40 µg View All» Format: Purified View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-131041.htm
      © Merck Millipore代理MAB3402 Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5;抗神经胶质纤维酸性蛋白抗体，克隆GA5store at +2℃ to +8℃，产品报价联系微信jinshanbio